Objective: To define the level of nitric oxide (NO) in the spermatic vein of patients with varicocele and its relation with male infertility.
Materials and Methods: Following physical and color Doppler ultrasonographic examination, whole blood samples were drawn from a peripheral vein and a dilated varicocele vein from fourteen patients with clinically palpable varicocele (G2–3) before ligation. NO levels in the serum were determined as total nitrite by Greiss reaction and results were compared with Mann–Whitney U test.
Results: NO levels in the internal spermatic vein were 36.05 ± 8.92 μmol/l, compared to 19.41 ± 4.12 μmol/l in the peripheral vein and the difference was statistically significant (p < 0.01).
Conclusion: In view of our results, increased NO levels in the dilated varicocele vein might be responsible for spermatozoa dysfunction.
Zafer mahallesi, Korukent Sitesi
A Blok, Daire no: 10
TR–44100 Malatya (Turkey)
Tel. +90 422 326 2053, Fax +90 422 341 0610
Accepted after revision: June 8, 1999
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 1, Number of References : 34
Official Organ of the European Association of Urology
Vol. 37, No. 2, Year 2000 (Cover Date: February 2000)
Journal Editor: C.C. Schulman, Brussels
ISSN: 0302–2838 (print), 1421–993X (Online)
For additional information: http://www.karger.ch/journals/eur
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