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Vol. 42, No. 4, 2009
Issue release date: June 2009
Section title: Original Paper
Psychopathology 2009;42:257–263
(DOI:10.1159/000224149)

Gender Differences in Axis I and Axis II Comorbidity in Patients with Borderline Personality Disorder

Tadić A. · Wagner S. · Hoch J. · Başkaya Ö. · von Cube R. · Skaletz C. · Lieb K. · Dahmen N.
Departments of aPsychiatry and bPsychology, University of Mainz, Mainz, cClinic of Psychiatry, Riedstadt, and dClinic of Psychiatry, Katzenelnbogen, Germany

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 6/30/2008
Accepted: 11/25/2008
Published online: 6/12/2009

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP

Abstract

Background/Aims: Differences in the clinical presentation of men and women with borderline personality disorder (BPD) are of potential interest for investigations into the neurobiology, genetics, natural history, and treatment response of BPD. The purpose of this study was to investigate gender differences in axis I and axis II comorbidity and in diagnostic criteria in BPD patients. Methods: 110 women and 49 men with BPD were assessed with the computer-based version of the Munich-Composite International Diagnostic Interview and the Structured Clinical Interview for DSM-IV Personality Disorders. Gender differences were investigated for the following outcomes: (a) lifetime, 12-month and 4-week prevalence of axis I disorders; (b) axis II disorders, and (c) DSM-IV BPD diagnostic criteria. Results: With regard to lifetime prevalence of axis I disorders, men more often displayed a substance use disorder, in particular alcohol dependency (65 vs. 43%); on the other hand, women more frequently had an affective (94 vs. 82%), anxiety (92 vs. 80%) or eating disorder (35 vs. 18%), in particular anorexia nervosa (21 vs. 4%). Regarding the 12-month prevalence, we found significantly more women suffering from anorexia nervosa (13 vs. 0%). Considering the 4-week prevalence, there were no significant gender differences. With regard to axis II disorders, men had a higher frequency of antisocial personality disorder (57 vs. 26%). Regarding the BPD diagnostic criteria, men more often displayed ‘intensive anger’ (74 vs. 49%), whereas women more frequently showed ‘affective instability’ (94 vs. 82%). Conclusion: In this German study, we could replicate and extend the findings from previous US studies, where men and women with BPD showed important differences in their pattern of psychiatric comorbidity. The implications for clinicians and researchers are discussed.


  

Author Contacts

André Tadić, MD
Department of Psychiatry, University of Mainz
Untere Zahlbacher Strasse 8
DE–55131 Mainz (Germany)
Tel. +49 6131 17 3950, Fax +49 6131 17 6690, E-Mail tadic@uni-mainz.de

  

Article Information

Received: June 30, 2008
Accepted after revision: November 25, 2008
Published online: June 12, 2009
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 4, Number of References : 29

  

Publication Details

Psychopathology (International Journal of Descriptive and Experimental Psychopathology, Phenomenology and Psychiatric Diagnosis)

Vol. 42, No. 4, Year 2009 (Cover Date: June 2009)

Journal Editor: Mundt C. (Heidelberg), Akiskal H.S. (San Diego, Calif.), Mezzich J.E. (New York, N.Y.)
ISSN: 0254-4962 (Print), eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 6/30/2008
Accepted: 11/25/2008
Published online: 6/12/2009

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


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