Journal Mobile Options
Table of Contents
Vol. 78, No. 5, 2009
Issue release date: August 2009
Section title: Special Article
Psychother Psychosom 2009;78:275–284
(DOI:10.1159/000228248)

The Selection and Design of Control Conditions for Randomized Controlled Trials of Psychological Interventions

Mohr D.C. · Spring B. · Freedland K.E. · Beckner V. · Arean P. · Hollon S.D. · Ockene J. · Kaplan R.
aDepartment of Preventive Medicine, Northwestern University, Chicago, Ill., bHines VA Medical Center, Hines, Ill., cDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Mo., dDepartment of Psychiatry, University of California, San Francisco, Calif., eDepartment of Psychology, Vanderbilt University, Nashville, Tenn., fUniversity of Massachusetts Medical School, Worchester, Mass., and gSchool of Public Health, University of California, Los Angeles, Calif., USA

Do you have an account?

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger (new!)
  • Unrestricted printing, no saving restrictions for personal use
  • Reduced rates with a PPV account
read more

Direct: USD 38.00
Account: USD 26.50

Select

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe

  • Automatic perpetual access to all articles of the subscribed year(s)
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select


Article / Publication Details

First-Page Preview
Abstract of Special Article

Received: 6/17/2008
Accepted: 10/31/2008
Published online: 7/11/2009

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 1

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS

Abstract

The randomized controlled trial (RCT) provides critical support for evidence-based practice using psychological interventions. The control condition is the principal method of removing the influence of unwanted variables in RCTs. There is little agreement or consistency in the design and construction of control conditions. Because control conditions have variable effects, the results of RCTs can depend as much on control condition selection as on the experimental intervention. The aim of this paper is to present a framework for the selection and design of control conditions for these trials. Threats to internal validity arising from modern RCT methodology are reviewed and reconsidered. The strengths and weaknesses of several categories of control conditions are examined, including the ones that are under experimental control, the ones that are under the control of clinical service providers, and no-treatment controls. Considerations in the selection of control conditions are discussed and several recommendations are proposed. The aim of this paper is to begin to define principles by which control conditions can be selected or developed in a manner that can assist both investigators and grant reviewers.


  

Author Contacts

David C. Mohr, PhD
Department of Preventive Medicine, Northwestern University
680 N. Lakeshore Dr., Suite 1220
Chicago, IL 60611 (USA)
Tel. +1 312 503 1403, E-Mail d-mohr@northwestern.edu

  

Article Information

Received: June 17, 2008
Accepted after revision: October 31, 2008
Published online: July 11, 2009
Number of Print Pages : 10
Number of Figures : 0, Number of Tables : 1, Number of References : 48

  

Publication Details

Psychotherapy and Psychosomatics

Vol. 78, No. 5, Year 2009 (Cover Date: August 2009)

Journal Editor: Fava G.A. (Bologna)
ISSN: 0033-3190 (Print), eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS


Article / Publication Details

First-Page Preview
Abstract of Special Article

Received: 6/17/2008
Accepted: 10/31/2008
Published online: 7/11/2009

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 1

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.