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Vol. 78, No. 2, 1985
Issue release date: 1985
Section title: Original Paper
Int Arch Allergy Immunol 1985;78:132–138
(DOI:10.1159/000233875)

Neutrophil and Monocyte Adherence in Diabetes mellitus, Alcoholic Cirrhosis, Uraemia and Elderly Patients

Kelly M.K. · Brown J.M. · Thong Y.H.
aDepartment of Child Health, University of Queensland, and bDepartment of Medicine, Mater Adult Hospital, South Brisbane, Qld, Australia

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/6/1984
Published online: 8/4/2009
Issue release date: 1985

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA

Abstract

The neutrophil and monocyte adherence were assessed in patients with diseases which predispose them to increased risk of infections. Neutrophil adherence was found to be markedly impaired in diabetes mellitus, alcoholic cirrhosis and uraemia. Monocyte adherence was also depressed in patients with diabetes mellitus and alcoholic cirrhosis, but not in patients with uraemia. Thus, the increased susceptibility of these categories of patients to infection can be explained in part by a defect in adherence. In contrast, neutrophil and monocyte adherence in elderly patients were comparable to that in healthy young adults, which confirms previous observations that the age-dependent decline in immunological function affects mainly the T and B cell systems.


  

Author Contacts

Correspondence to: Dr. Y.H. Thong, Department of Child Health, University of Queensland, Mater Children’s Hospital, South Brisbane Qld 4101 (Australia)

  

Article Information

Received: December 6, 1984
Published online: August 04, 2009
Number of Print Pages : 7

  

Publication Details

International Archives of Allergy and Immunology

Vol. 78, No. 2, Year 1985 (Cover Date: 1985)

Journal Editor: Valenta R. (Vienna)
ISSN: 1018-2438 (Print), eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 12/6/1984
Published online: 8/4/2009
Issue release date: 1985

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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