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Table of Contents
Vol. 94, No. 1-4, 1991
Issue release date: 1991
Section title: Allergens and Their Characterization
Int Arch Allergy Immunol 1991;94:346–348
(DOI:10.1159/000235399)

Allergen Profiles of Dog Hair and Dander, Body Fluids and Tissues as Defined by Immunoblotting

Spitzauer S.a · Rumpold H.a · Ebner Ch.b · Schweiger Ch.a · Valenta R.b · Gabl F.a · Anrather J.c · Breitenbach M.d · Scheiner O.b · Kraft D.b
aInstitue of Clinical Chemistry and Laboratory Diagnostics; bInstitute of General and Experimental Pathology; cClinic of Veterinary Medicine, Department of Internal Medicine, and dInstitute of Microbiology and Genetics, University of Vienna, Austria

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Article / Publication Details

First-Page Preview
Abstract of Allergens and Their Characterization

Published online: August 07, 2009
Issue release date: 1991

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA

Abstract

The sera from 25 patients with clinical type I allergy against dogs were investigated by means of immunoblotting, using extracts of dog hair/dander, skin, hair, saliva, salivary gland, serum and liver. 96% of the patients’ sera showed IgE antibodies reactive with 19- and 23-kilodalton (kDa) proteins in the hair/dander extract. The 23-kDa IgE-binding protein was preferentially detected in the hair extract and saliva but not in skin, salivary gland, serum and liver extracts. The 19-kDa band was strongly expressed in skin, but not in hair, serum and liver. Inhibition experiments using the 23-kDa containing extract prepared from hair and the 19-kDa containing extract prepared from skin revealed that these two proteins are likely to be immunologically independent allergens.

© 1991 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Allergens and Their Characterization

Published online: August 07, 2009
Issue release date: 1991

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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