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Table of Contents
Vol. 106, No. 2, 1995
Issue release date: 1995
Section title: Original Paper
Int Arch Allergy Immunol 1995;106:149–156
(DOI:10.1159/000236836)

Prevalence of Atopy and Pollinosis in the Adult Population of Switzerland (SAPALDIA Study)

Wüthrich B.a · Schindler C.b · Leuenberger P.c · Ackermann-Liebrich U.b
aAllergy Unit, Department of Dermatology, University Hospital Zurich, bInstitute of Social and Preventive Medicine, University of Basel, and cDivision of Pneumology, University of Lausanne, Switzerland

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 14, 1994
Accepted: September 27, 1994
Published online: September 04, 2009
Issue release date: 1995

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA

Abstract

The Swiss SAPALDIA study is a large multicenter cross-sectional study initiated in 1991 to evaluate the relationship between environment and respiratory symptoms and diseases in adults, and included subjects from eight areas in Switzerland with distinctive environmental characteristics. We present here prevalence data for atopy, pollinosis and atopic asthma obtained from a random sample of 8,357 adults (18–60 years) assessed by standardized computer-based interview as well as by allergy skin prick tests (SPTs) (performed with Phazet) to grass, birch and Parietaria pollen, house dust mite, cat and dog epithelia and the moulds Alternaria and Cladosporium and by an in vitro allergy screen test (Phadiatop CAP FEIA system). On the basis of a positive Phadiatop (total 28.9%; males 32.9%, females 25.0%; p < 0.001) and/or a positive SPT (total 23%; males 25.0%, females 20.8%; p < 0.001), 32.3% of the study population were considered atopic (males 35.7%, females 28.8%; p < 0.001). Concerning the prevalence of skin sensitization (SPT wheal ≥ 3 mm), the highest rate was observed for grass (12.7%), followed by house dust mite (8.9%), silver birch (7.9%), cat (3.8%) and dog (2.8%), whereas moulds and Parietaria elicited less than 1% positive SPTs. The prevalence of atopic rhinitis (rhinitis symptoms associated with atopy) was 13.5% (males 14.3%, females 12.6%; p < 0.05) and the prevalence of current hay fever varied between 9.1% (questionnaire answer and a positive SPT to at least one pollen), 11.2% (questionnaire answer and presence of atopy) to 14.2% (questionnaire answer only) with no significant difference by sex. However, a significant difference for the prevalence rate of hay fever was observed between Swiss citizens with 11.6% and foreign citizens living in Switzerland with 8.7% (p < 0.01). Pollen-induced asthma (seasonal asthma symptoms and presence of a positive SPT to pollen) was judged to be present in at least 4.3%. These data confirm the high rate of atopy and atopic respiratory diseases in a western country. Taking into consideration the main differences in prevalence rates recorded in 1926 (0.82%), 1958 (4.8%) and 1986 (9.6%), the present survey demonstrates a further increase in self-reported current hay fever in Switzerland.

© 1995 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 14, 1994
Accepted: September 27, 1994
Published online: September 04, 2009
Issue release date: 1995

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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