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Table of Contents
Vol. 111, No. 1, 1996
Issue release date: 1996
Section title: Original Paper
Int Arch Allergy Immunol 1996;111:55–63
(DOI:10.1159/000237346)

IgA and IgG Binding Components of Wheat, Rye, Barley and Oats Recognized by Immunoblotting Analysis with Sera from Adult Atopic Dermatitis Patients

Varjonen E.a · Kalimo K.b · Savolainen J.c · Vainio E.b
aDepartment of Dermatology, Helsinki University Central Hospital, and Departments of bDermatology and cClinical Allergology, Turku University Central Hospital, Finland

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 05, 1995
Accepted: March 05, 1996
Published online: September 04, 2009
Issue release date: 1996

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA

Abstract

IgA and IgG antibody response of adult atopic dermatitis patients against neutral/acidic fractions of wheat, rye, barley and oats was analyzed utilizing an immunoblotting method. Moreover, the antibody response against ethanol-soluble fraction of wheat was examined with serum pools of healthy donors, atopic dermatitis patients and patients with dermatitis herpetiformis or adult celiac disease. All patient sera revealed polymorphic IgA and IgG binding to cereal peptides with molecular weights of 11–97 kD. The antibody staining was essentially identical with atopic dermatitis patients and controls. Patients with dermatitis herpetiformis or celiac disease showed more intensive staining with the ethanol extract of wheat and showed more IgA-stained bands in immunoblotting. It seems that the presence of IgA and IgG antibodies to different cereal antigens is a result of natural exposure and in atopic dermatitis displays little diagnostic significance, in contrast to antigliadin antibody response in dermatitis herpetiformis and celiac disease.

© 1996 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 05, 1995
Accepted: March 05, 1996
Published online: September 04, 2009
Issue release date: 1996

Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


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