Noninvasive Home Mechanical Ventilation in Elderly PatientsCrespo A. · Muñoz X. · Torres F. · Martí S. · Ferrer J. · Morell F.
aServei de Pneumologia, Hospital Universitari Vall d’Hebron, bDepartament de Biologia Celular, Fisiologia, Inmunologia, Facultat de Medicina, cDepartament de Medicina, i dLaboratori de Bioestadística i Epidemiologia, Universitat Autónoma de Barcelona, Barcelona, España
Study Objective: To determine the short- and long-term benefits of noninvasive home mechanical ventilation (NIHMV) in patients aged 65 and older who were eligible for this treatment. Design and Setting: This retrospective, comparative, longitudinal study was carried out in a tertiary care hospital in Barcelona (Spain). Patients and Methods: The study included all patients in whom NIHMV with a nasal mask was established in the period from 1998 to 2001. Patients were divided into 3 groups according to age: group 1 (n = 10) ≧75; group 2 (n = 40) 65–74, and group 3 (n = 41) <65 years old. Clinical characteristics, pulmonary function results, and arterial blood gas findings were assessed in all patients before starting ventilation and after 6 months. Measurements and Results: Statistically significant improvements in PaO2 (13.4, 10, and 15.3 mm Hg for groups 1–3) and PaCO2 (–17.6, –9.6 and –12.8 mm Hg for groups 1–3) were found at 6 months (p < 0.001 in all cases). There were no significant differences between the groups in blood gas parameters and treatment compliance. The incidence of related adverse events was not statistically different between the study groups (40%, 35% and 32% for groups 1–3; p = 0.859). Conclusions: NIHMV is effective in all patients for whom it is indicated, regardless of their age.
Dr. Xavier Muñoz
Servei de Pneumologia, Hospital General Vall d’Hebron
Passeig Vall d’Hebron, 119
ES–08035 Barcelona (Spain)
Tel. +34 93 274 6157, Fax +34 93 274 6083, E-Mail firstname.lastname@example.org
A.C. and X.M. contributed equally to this study, which is part of the doctoral thesis of A.C.
Received: March 20, 2009
Accepted: May 28, 2009
Published online: September 10, 2009
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 5, Number of References : 20
Gerontology (International Journal of Experimental, Clinical, Behavioural and Technological Gerontology)
Vol. 56, No. 2, Year 2010 (Cover Date: March 2010)
Journal Editor: Wick G. (Innsbruck)
ISSN: 0304-324X (Print), eISSN: 1423-0003 (Online)
For additional information: http://www.karger.com/GER