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Table of Contents
Vol. 54, No. 2, 1988
Issue release date: 1988
Section title: Original Paper
Biol Neonate 1988;54:100–106
(DOI:10.1159/000242831)

Lung Glycogen Metabolism in Suckling Rats: A Comparative Study

Maritz G.S.
Department of Physiological Sciences, University of the Western Cape, Bellville, South Africa

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: September 25, 2009
Issue release date: 1988

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: http://www.karger.com/NEO

Abstract

Glycogen metabolism was studied in lungs of suckling rats and the data was compared with that of the adult. From the data it appeared that the control of glycogen metabolism of lung tissue of suckling rats differs from that of adult lung. After a 24-hour fasting period, the lung glycogen content of 1- to 2-week-old rats was decreased (p < 0.05). This was accompanied by an increased (10%) phosphorylase activity (p < 0.001). In contrast to this, the lung glycogen content of adult lung increased by about 26% (p < 0.05) while at the same time the hexokinase activity increased by about 39% and the phosphorylase activity decreased by about 65%. Also, the 1- to 2-week-old lung utilized glycogen more readily (9.00 ± 0.04 μmol/g/h) than adult lung (3.70 ± 0.15 μmol/g/h). This means that lung tissue of suckling rats is more dependent on glycogen than adult lung which is probably the reason for the difference in control.

© 1988 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: September 25, 2009
Issue release date: 1988

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: http://www.karger.com/NEO


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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