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Table of Contents
Vol. 53, No. 1, 2010
Issue release date: January 2010
Section title: Original Article
Intervirology 2010;53:76–81

Non-Invasive Evaluation of Hepatic Fibrosis for Type C Chronic Hepatitis

Tatsumi C.a · Kudo M.a · Ueshima K.a · Kitai S.a · Ishikawa E.a · Yada N.a · Hagiwara S.a · Inoue T.a · Minami Y.a · Chung H.a · Maekawa K.b · Fujimoto K.c · Kato M.c · Tonomura A.d · Mitake T.d · Shiina T.e
aDepartment of Gastroenterology and Hepatology, Kinki University School of Medicine, and bDivision of Abdominal Ultrasound, Department of Laboratory Medicine, Kinki University School of Medicine, Osaka-Sayama, cDepartment of Internal Medicine, National Hospital Organization Minami-Wakayama Medical Center, Tanabe, dHitachi Medical Corporation, Tokyo, and eHuman Health Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan
email Corresponding Author

Masatoshi Kudo, MD, PhD, Division of Gastroenterology and Hepatology

Department of Internal Medicine, Kinki University School of Medicine

377-2, Ohno-Higashi, Osaka-Sayama 589-8511 (Japan)

Tel. +81 72 366 0221, ext. 3149, Fax +81 72 367 2880

E-Mail m-kudo@med.kindai.ac.jp

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Objective: The aim of this study was to investigate liver fibrosis using non-invasive Real-time Tissue Elastography® (RTE) and transient elastography (FibroScan®) methods. Methods: RTE, FibroScan and percutaneous liver biopsy were all performed on patients with chronic liver disease, particularly hepatitis C, to investigate liver fibrosis. Results: FibroScan and RTE were compared for fibrous liver staging (F stage), which was pathologically classified using liver biopsy. In FibroScan, significant differences were observed between F1/F3 and F2/F4, but no such differences were observed between F1/F2, F2/F3 and F3/F4. In RTE, significant differences were observed between F1/F2, F2/F3 and F2/F4. But for F3/F4, no significant differences were observed. Conclusion: FibroScan and RTE correlated well with F staging of the liver. In particular RTE was more successful than FibroScan in diagnosing the degree of liver fibrosis.

© 2010 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Original Article

Published online: January 05, 2010
Issue release date: January 2010

Number of Print Pages: 6
Number of Figures: 8
Number of Tables: 0

ISSN: 0300-5526 (Print)
eISSN: 1423-0100 (Online)

For additional information: http://www.karger.com/INT

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