Journal Mobile Options
Table of Contents
Vol. 19, No. 4, 1985
Issue release date: 1985
Caries Res 1985;19:379–384
Clinical Science

The Use of Fibre-Optic Transillumination in the Diagnosis of Posterior Approximal Caries in Clinical Trials

Mitropoulos C.M.
Dental Health Unit, Department of Child Dental Health, University Dental Hospital of Manchester, UK


The need to develop alternative techniques other than bitewing radiographs for the diagnosis of caries in clinical trials is discussed and the use of fibre-optic transillumination (FOTI) proposed. A validation study was conducted in which the teeth of 25, 12- to 13-year-old children were examined using a direct-light source, by FOTI and by bitewing radiographs for the presence of dentinal lesions on posterior approximal surfaces. Taking diagnoses from radiographs as the validating criteria, the sensitivity of FOTI was 0.73 and specificity 0.99. A clinical trial involving 224, 12- to 13-year-old children was established to compare the efficacy of two fluoride dentifrices, FOTI being incorporated into the clinical examination. Use of FOTI increased the discriminatory ability of the clinical examination such that the percent caries change in efficacy detected between the two dentifrices rose from 5 to 10% for the DFS index and from 14 to 19% for DMFT. FOTI is proposed as a valid, efficient alternative to bitewing radiographs in clinical trials of caries-prophylactic agents.

 goto top of outline Author Contacts

Dr. C.M. Mitropoulos, University of Manchester, Turner Dental School, Bridgeford Street, Manchester M15 6FH (UK)

 goto top of outline Article Information

Published online: November 18, 2009
Number of Print Pages : 6

 goto top of outline Publication Details

Caries Research

Vol. 19, No. 4, Year 1985 (Cover Date: 1985)

Journal Editor: Shellis R.P. (Bristol)
ISSN: 0008-6568 (Print), eISSN: 1421-976X (Online)

For additional information:

Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.