The need to develop alternative techniques other than bitewing radiographs for the diagnosis of caries in clinical trials is discussed and the use of fibre-optic transillumination (FOTI) proposed. A validation study was conducted in which the teeth of 25, 12- to 13-year-old children were examined using a direct-light source, by FOTI and by bitewing radiographs for the presence of dentinal lesions on posterior approximal surfaces. Taking diagnoses from radiographs as the validating criteria, the sensitivity of FOTI was 0.73 and specificity 0.99. A clinical trial involving 224, 12- to 13-year-old children was established to compare the efficacy of two fluoride dentifrices, FOTI being incorporated into the clinical examination. Use of FOTI increased the discriminatory ability of the clinical examination such that the percent caries change in efficacy detected between the two dentifrices rose from 5 to 10% for the DFS index and from 14 to 19% for DMFT. FOTI is proposed as a valid, efficient alternative to bitewing radiographs in clinical trials of caries-prophylactic agents.
Dr. C.M. Mitropoulos, University of Manchester, Turner Dental School, Bridgeford Street, Manchester M15 6FH (UK)
Published online: November 18, 2009
Number of Print Pages : 6
Vol. 19, No. 4, Year 1985 (Cover Date: 1985)
Journal Editor: Shellis R.P. (Bristol)
ISSN: 0008-6568 (Print), eISSN: 1421-976X (Online)
For additional information: http://www.karger.com/CRE
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