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Table of Contents
Vol. 123, No. 1, 2010
Issue release date: December 2009
Section title: Case Report
Acta Haematol 2010;123:30–33
(DOI:10.1159/000261020)

Granulomatous Pneumocystis jiroveci Pneumonia in a Patient with Diffuse Large B-Cell Lymphoma: Case Report and Review of the Literature

Chang H.a, b · Shih L.-Y.a, b · Wang C.-W.c · Chuang W.-Y.c · Chen C.-C.d
aChang Gung University School of Medicine, Taoyuan, bDivision of Hematology-Oncology, and Departments of cPathology and dRadiology,Chang Gung Memorial Hospital, Taipei, Taiwan, ROC

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: July 02, 2009
Accepted: September 23, 2009
Published online: November 25, 2009
Issue release date: December 2009

Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 1

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: http://www.karger.com/AHA

Abstract

Here we report a case of diffuse large B-cell lymphoma who developed granulomatous Pneumocystis jiroveci pneumonia (PJP) after rituximab and combination chemotherapy. The infection presented as a solitary pulmonary nodule (SPN) instead of the commonly seen diffuse ground-glass infiltrates. The diagnosis was made by wedge resection of the nodule. Both the CD4+ lymphocyte count and immunoglobulin level were low. A literature search revealed 14 granulomatous PJP patients with hematological neoplasms, including the present case, which was the first with diffuse large B-cell lymphoma and the only patient receiving rituximab before PJP development. In addition to our report, only one case had previously presented with an SPN. Our experience suggests that granulomatous PJP should be considered a possible etiology when immunocompromised patients develop fever and SPNs.

© 2009 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: July 02, 2009
Accepted: September 23, 2009
Published online: November 25, 2009
Issue release date: December 2009

Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 1

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: http://www.karger.com/AHA


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