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Vol. 114, No. 3, 2010
Issue release date: February 2010
Section title: Original Paper
Nephron Clin Pract 2010;114:c178–c186
(DOI:10.1159/000262300)

Determinants of Resistive Index Shortly after Transplantation: Independent Relationship with Delayed Graft Function

Rodrigo E.a · López-Rasines G.b · Ruiz J.C.a · Lastra P.b · Gómez-Dermitt V.b · Gómez-Alamillo C.a · González-Cotorruelo J.a · Calabia A.b · Arias M.a
aService of Nephrology and bDepartment of Radiology, University Hospital Valdecilla, University of Cantabria, Santander, Spain

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 6/16/2009
Accepted: 9/4/2009
Published online: 11/28/2009
Issue release date: February 2010

Number of Print Pages: 1
Number of Figures: 3
Number of Tables: 3

ISSN: (Print)
eISSN: 1660-2110 (Online)

For additional information: http://www.karger.com/NEC

Abstract

Measurement of the vascular resistive index (RI) by Doppler ultrasonography has been proposed as a non-invasive method to evaluate renal allograft dysfunction, but there are conflicting reports about its clinical utility. The aim of our study was to analyse the donor and recipient characteristics related to RI measured at days 2 and 3 after renal transplantation and the relationship between RI and allograft outcome. RI was measured by Doppler ultrasonography in 333 patients at days 2 or 3 post-transplantation. Donor and recipient variables and allograft outcome were collected from a prospectively maintained institutional database. In patients with RI higher than 0.7, donor age, recipient age, duration of renal replacement therapy, incidence of diabetes, hypertension and atherosclerosis in the recipient, pulse pressure, initial creatinine and the incidence of delayed graft function (DGF) were higher. After multivariate analysis, the only variables that remained significant for an increased risk of higher RI were recipient age over 55 years, presence of diabetes in the recipient and DGF. Recipient age, previous diabetes mellitus and DGF are the most important determinants of transplant kidney RI in the first days after transplantation. So both the graft recipient and the graft itself, but not the donor, determine intra-renal Doppler indices.

© 2009 S. Karger AG, Basel


  

Author Contacts

Emilio Rodrigo
Servicio de Nefrología
Hospital Universitario ‘Marqués de Valdecilla’, Servicio Cántabro de Salud
ES–39008 Santander (Spain)
Tel. +34 94 220 2738, Fax +34 94 232 0415, E-Mail nefrce@humv.es

  

Article Information

Received: June 16, 2009
Accepted: September 4, 2009
Published online: November 28, 2009
Number of Print Pages : 9
Number of Figures : 3, Number of Tables : 3, Number of References : 36

  

Publication Details

Nephron Clinical Practice

Vol. 114, No. 3, Year 2010 (Cover Date: February 2010)

Journal Editor: El Nahas M. (Sheffield)
ISSN: 1660-2110 (Print), eISSN: 1660-2110 (Online)

For additional information: http://www.karger.com/NEC


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 6/16/2009
Accepted: 9/4/2009
Published online: 11/28/2009
Issue release date: February 2010

Number of Print Pages: 1
Number of Figures: 3
Number of Tables: 3

ISSN: (Print)
eISSN: 1660-2110 (Online)

For additional information: http://www.karger.com/NEC


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