Neurochemical Substrates and Neuroanatomical Generators of the Event-Related P300Frodl-Bauch T. · Bottlender R. · Hegerl U.
Department of Clinical Neurophysiology and Department of Psychiatry, Ludwig-Maximilians-Universität München, Deutschland
The present review focuses on the current knowledge of the neurochemical processes and neuronal structures involved in the generation of P300. The increasing knowledge in this area facilitates the physiological interpretation of P300 findings as well as the link between P300 research and other research findings in biological psychiatry. Concerning the question of neurochemical substrates, the glutamatergic, GABAergic, cholinergic, noradrenergic, dopaminergic and serotonergic influences on P300 are reviewed. The knowledge of the generating structures of P300 is summarized from intracranial studies, magnetoencephalographic investigations, lesion and animal studies.
Department of Psychiatry, Department of Clinical Neurophysiology, EEG
Nussbaumstrasse 7, D–80336 Munich (Germany)
Tel. +49 89 5160 3409, E-Mail Thomas.Frodl-Bauch@psy.med.uni-muenchen.de
Number of Print Pages : 9
Number of Figures : 2, Number of Tables : 0, Number of References : 86
Neuropsychobiology (International Journal of Experimental and Clinical Research in Biological Psychiatry, Pharmacopsychiatry, Biological Psychology/Pharmacopsychology and Pharmacoelectroencephalography)
Founded 1975 by J. Mendlewicz (Brussels)
Official Journal of the International Pharmaco-EEG Society (IPEG)
Vol. 40, No. 2, Year 1999 (Cover Date: Released August 1999)
Journal Editor: J. Mendlewicz, Brussels; B. Saletu, Vienna; P. Netter, Giessen; W.M. Herrmann, Berlin
ISSN: 0302–282X (print), 1423–0224 (Online)
For additional information: http://www.karger.com/journals/nps