Severe anaphylaxis to contrast media used in hysterosalpingography is very rare. Leukopenia may sometimes be seen in severe anaphylaxis associated with shock. This case report is about an atypical presentation of anaphylaxis following the injection of Conray 280 for hysterosalpingography. The patient had severe leukopenia without other associated features of anaphylaxis that resolved spontaneously after 48 h. This type of reaction to Conray 280 has not been reported before.
- Forsey JP, Caul EO, Paul ID, Hull MG: Chlamydia trachomatis, tubal disease and the incidence of symptomatic and asymptomatic infection following hysterosalpingography. Hum Reprod 1990;5:444–447.
- Elias J: Systemic reaction to radiocontrast media during hysterodalpingography. J Allergy Clin Immunol 1980;66:242.
- Capdeville R, Remy J: A major complication of hysterosalpingography. J Radiol 1983;64:561–562.
- Schuitemaker NW, Helmerhorst FM, Tjon ATRT, van Saase JL: Late anaphylactic shock after hysterosalpingography. Fertil Steril 1990;54:535–536.
- Eisenberg AD, Winfield AC, Page DL, Holburn GE, Schifter T, Segars JH: Peritoneal reaction resulting from iodinated contrast material: comparative study. Radiology 1989;172:149–151.
- Davies AC, Keightley A, Borthwick-Clarke A, Walters HL: The use of a low-osmolality contrast medium in hysterosalpingography: comparison with a conventional contrast medium. Clin Radiol 1985;36:533–536.
- Thurmond AS, Hedgpeth PL, Scanlan RM: Selective injection of contrast media: inflammatory effects on rabbit fallopian tubes. Radiology 1991;180:97–99.
- Moore DE, Segars JH, Jr, Winfield AC, Page DL, Eisenberg AD, Holburn GE: Effects of contrast agents on the fallopian tube in a rabbit model. Radiology 1990;176:721–744.
- Winfield AC, Henderson-Slayden R, Wentz AC, Harding DR: Hysterosalpingography: comparison of Conray 60 and Sinografin. AJR Am J Roentgenol 1982;138:559–560.
- Parker CW. Allergic reactions in man. Pharmacol Rev 1982;34:85–104.
- Wells PW, Eyre P, Lumsden JH: Hematological and pathological changes in acute systemic anaphylaxis in calves: effects of pharmacological agents. Can J Comp Med 1973;37:119–129.
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Received: March 10, 2009
Accepted after revision: October 27, 2009
Published online: December 21, 2009
Number of Print Pages : 3
Number of Figures : 0, Number of Tables : 1, Number of References : 11
Gynecologic and Obstetric Investigation
Vol. 69, No. 3, Year 2010 (Cover Date: April 2010)
Journal Editor: D'Hooghe T. (Leuven)
ISSN: 0378-7346 (Print), eISSN: 1423-002X (Online)
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