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Vol. 69, No. 3, 2010
Issue release date: April 2010
Section title: Case Report
Gynecol Obstet Invest 2010;69:212–216
(DOI:10.1159/000274467)

Vulvar Lymphoedematous Pseudotumours Mistaken for Aggressive Angiomyxoma: Report of Two Cases

D’Antonio A. · Caleo A. · Boscaino A. · Mossetti G. · Iannantuoni N.
aUnit of Pathologic Anatomy, A.U.O. San Giovanni di Dio e Ruggi d’Aragona, Salerno, bUnit of Pathologic Anatomy, Casa di Cura Maria Rosaria, Pompei, cUnit of Pathologic Anatomy, A.O.R.N. Cardarelli, Naples, and dDepartment of Gynecology and Obstetrics, San Giuliano Hospital, Giugliano, Italy

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 3/18/2009
Accepted: 11/9/2009
Published online: 1/12/2010

Number of Print Pages: 5
Number of Figures: 5
Number of Tables: 2

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI

Abstract

Background: We describe 2 cases of vulvar pseudotumour due to lymphatic obstruction with chronic lymphoedema of unknown cause that presented as a solitary mass that mimicked aggressive angiomyxoma. Material and Methods: Both patients presented with a vulvar mass without medical history of trauma, surgery in the anogenital region or skin diseases. One patient was overweight (BMI = 26). Both surgically resected vulvar specimens were represented by a polypoid mass with a soft and a gelatinous cut surface. Results: Histologically, the presence of an abundant oedematous stroma with spindle-shaped cells and numerous thin-walled small-to-medium vessels may be confused with an aggressive angiomyxoma. The diagnostic key was represented by the massive oedema, rather than myxoid stroma, with the presence of dilated, tortuous lymphatic channels (some surrounded by clusters of lymphocytes) in the dermis. Conclusion: The recognition of these lesions is important because they may be the cause of problems in differential diagnosis and therapeutic management. In fact, such lesions can be mistaken from both the clinical and histological perspective as a primitive tumour of the vulva-like aggressive angiomyxoma. However, these lesions are not true neoplasms and are likely due to lymphatic obstruction with lymphoedema. A simple surgical excision with vulvoplasty is curative.


  

Author Contacts

Antonio D’Antonio, MD, PhD
Unit of Pathologic Anatomy, A.U.O
San Giovanni di Dio e Ruggi d’Aragona
IT–84131 Salerno (Italy)
Tel. +39 089 672 367, Fax +39 081 747 3550, E-Mail ada66@inwind.it

  

Article Information

Received: March 18, 2009
Accepted after revision: November 9, 2009
Published online: January 12, 2010
Number of Print Pages : 5
Number of Figures : 5, Number of Tables : 2, Number of References : 5

  

Publication Details

Gynecologic and Obstetric Investigation

Vol. 69, No. 3, Year 2010 (Cover Date: April 2010)

Journal Editor: D'Hooghe T. (Leuven)
ISSN: 0378-7346 (Print), eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI


Article / Publication Details

First-Page Preview
Abstract of Case Report

Received: 3/18/2009
Accepted: 11/9/2009
Published online: 1/12/2010

Number of Print Pages: 5
Number of Figures: 5
Number of Tables: 2

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI


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