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Vol. 25, No. 1, 1992
Issue release date: 1992
Section title: Original Paper
Psychopathology 1992;25:49–56
(DOI:10.1159/000284753)

Measurement of Depression and Negative Symptoms in Schizophrenia

Goldman R.G. · Tandon R. · Liberzon I. · Greden J.F.
aSchizophrenia Program, University of Michigan Medical Center, and bVA Medical Center, Ann Arbor, Mich., USA

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 2/9/2010

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP

Abstract

The validity of the Hamilton Depression Scale (HAM-D) as a measure of depressive symptomatology in schizophrenic patients is questionable since it was not developed for this purpose, nor has it been validated in a schizophrenic population. Accordingly, 80 schizophrenic inpatients were administered the HAM-D, the 18-item Brief Psychiatric Rating Scale (BPRS), and the Scale for the Assessment of Negative Symptoms (SANS) at drug-free baseline and after 4 weeks of neuroleptic treatment. The findings revealed that the HAM-D total score was nonspecific, while individual HAM-D subfactors provided a better index of various symptom complexes. The HAM-D contained a depressive factor that correlated strongly with the BPRS depression factor and a negative symptom factor that correlated strongly with the SANS and the BPRS negative symptom factor. These findings suggest the need to utilize specific assessment techniques rather than global measures when assessing depression in schizophrenia.


  

Author Contacts

Robert S. Goldman, PhD, Veterans Administration Medical Center, Psychology Service (116B), 2215 Fuller Road, Ann Arbor, MI 48105 (USA)

  

Article Information

Published online: February 09, 2010
Number of Print Pages : 8

  

Publication Details

Psychopathology (International Journal of Descriptive and Experimental Psychopathology, Phenomenology and Psychiatric Diagnosis)

Vol. 25, No. 1, Year 1992 (Cover Date: 1992)

Journal Editor: Mundt C. (Heidelberg), Akiskal H.S. (San Diego, Calif.), Mezzich J.E. (New York, N.Y.)
ISSN: 0254-4962 (Print), eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 2/9/2010

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


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