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Vol. 25, No. 1, 1988
Issue release date: 1988
Section title: Original Paper
Gynecol Obstet Invest 1988;25:47–57
(DOI:10.1159/000293745)

Descriptive Light and Electron Microscopy of Normal and Clue-Cell-Positive Discharge

van der Meijden W.I.a · Koerten H.b · van Mourik W.c · de Bruijn W.C.b,c
aDepartment of Dermatology and Venereology, University Hospital ‘Dijkzigt’, Rotterdam; bLaboratory for Electron Microscopy, University of Leiden, and cDepartment of Clinical Pathology, Laboratory for Experimental Electron Microscopy, Erasmus University, Rotterdam, The Netherlands

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 2/25/1987
Accepted: 5/13/1987
Published online: 3/2/2010
Issue release date: 1988

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI

Abstract

In women with clue-cell-positive discharge (CCPD), light-microscopical examination of the wet mount suggests a preference of bacteria for certain vaginal epithelial cells (VECs). To investigate this further, a light- and electron-microscopical study of patients and healthy controls was performed, with special emphasis on vitality and glycogen content of VECs and bacterial-epithelial cell interaction. Our study did not reveal morphologic differences between VECs of patients and controls. There was, however, a significant decrease in the percentages of vital and glycogen-containing VECs in CCPD (p < 0.001), probably caused by an overgrowth of (anaerobic) bacteria. In CCPD vaginal bacteria preferably colonize vital VECs. This could account for the relatively low percentage of clue cells in this condition.

© 1988 S. Karger AG, Basel


  

Author Contacts

Dr. W.I. van der Meijden, Department of Dermatology and Venereology, University Hospital ‘Dijkzigt’, Dr. Molewaterplein 40, NL-3015 GD Rotterdam (The Netherlands)

  

Article Information

Received: February 25, 1987
Accepted: May 13, 1987
Published online: March 02, 2010
Number of Print Pages : 11

  

Publication Details

Gynecologic and Obstetric Investigation

Vol. 25, No. 1, Year 1988 (Cover Date: 1988)

Journal Editor: D'Hooghe T. (Leuven)
ISSN: 0378-7346 (Print), eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 2/25/1987
Accepted: 5/13/1987
Published online: 3/2/2010
Issue release date: 1988

Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: http://www.karger.com/GOI


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