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Table of Contents
Vol. 29, No. 5, 2010
Issue release date: June 2010
Section title: Original Research Article
Free Access
Dement Geriatr Cogn Disord 2010;29:413–423

Vegetables, Unsaturated Fats, Moderate Alcohol Intake, and Mild Cognitive Impairment

Roberts R.O.a · Geda Y.E.a, c · Cerhan J.R.a · Knopman D.S.d · Cha R.H.b · Christianson T.J.H.b · Pankratz V.S.b · Ivnik R.J.c · Boeve B.F.d · O’Connor H.M.e · Petersen R.C.a, d
Divisions of aEpidemiology and bBiomedical Statistics and Informatics, Department of Health Sciences Research, Departments of cPsychiatry and Psychology and dNeurology, and eOffice for Human Research Protection, College of Medicine, Mayo Clinic, Rochester, Minn., USA
email Corresponding Author

Dr. Rosebud O. Roberts

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic

200 First Street SW

Rochester, MN 55905 (USA)

Tel. +1 507 284 5656, Fax +1 507 284 1516, E-Mail roberts.rosebud@mayo.edu

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Background/Aims: To investigate associations of the Mediterranean diet (MeDi) components and the MeDi score with mild cognitive impairment (MCI). Methods: Participants (aged 70–89 years) were clinically evaluated to assess MCI and dementia, and completed a 128-item food frequency questionnaire. Results: 163 of 1,233 nondemented persons had MCI. The odds ratio of MCI was reduced for high vegetable intake [0.66 (95% CI = 0.44–0.99), p = 0.05] and for high mono- plus polyunsaturated fatty acid to saturated fatty acid ratio [0.52 (95% CI = 0.33–0.81), p = 0.007], adjusted for confounders. The risk of incident MCI or dementia was reduced in subjects with a high MeDi score [hazard ratio = 0.75 (95% CI = 0.46–1.21), p = 0.24]. Conclusion: Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.

© 2010 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: March 19, 2010
Published online: May 22, 2010
Issue release date: June 2010

Number of Print Pages: 11
Number of Figures: 1
Number of Tables: 5

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

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