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Vol. 4, No. 2, 2010
Issue release date: May – August
Open Access Gateway
Case Rep Gastroenterol 2010;4:298–303
Published: August 2010

Extrapulmonary Small Cell Carcinoma of the Stomach: A Lethal Entity

Moise D. · Singh J. · Dahl K. · Rashid S. · Prasad A. · Siddiqui G. · Subramani K. · Mustacchia P. · Rizvon K.
Department of Gastroenterology, Nassau University Medical Center, East Meadow, N.Y., USA


Extrapulmonary small cell carcinoma of the stomach is a rare and aggressive malignancy with a poor prognosis that was first described in 1976 by Matsusaka et al. In 1989 it was recognized by the World Health Organization as an independent entity affecting the stomach. Pure and composite are the two types of gastric small cell carcinoma reported in the literature. We report a case of a 68-year-old African American male with metastatic pure-type extrapulmonary small cell cancer of the stomach. The primary lesion measured approximately 7 cm in diameter on endoscopy. The diagnosis was made on the basis of characteristic histological features of small, round, oval lymphocyte-like cells with hyperchromatic nuclei, and scant cytoplasm consistent with small cell carcinoma. Gastric small cell carcinoma is typically diagnosed at an advanced stage as demonstrated in our case. We conducted a literature review discussing the two types of extrapulmonary small cell carcinoma of the stomach and their prevalence.

 goto top of outline Author Contacts

Kaleem Rizvon, MD
Department of Gastroenterology, Nassau University Medical Center
2201, Hempsted Turnpike, East Meadow, NY 11554 (USA)
Tel. +1 516 572 6501, Fax +1 516 572 5609, E-Mail

 goto top of outline Article Information

Published online: August 27, 2010
Number of Print Pages : 6
Number of Figures : 3, Number of Tables : 1,

 goto top of outline Publication Details

Case Reports in Gastroenterology

Vol. 4, No. 2, Year 2010 (Cover Date: May - August)

Journal Editor: Urrutia R. (Rochester, Minn.)
ISSN: NIL (Print), eISSN: 1662-0631 (Online)

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