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Vol. 44, No. 1, 2011
Issue release date: January 2011
Section title: Original Paper
Psychopathology 2011;44:12–20
(DOI:10.1159/000315362)

Outcomes of Empirical Eating Disorder Phenotypes in a Clinical Female Sample: Results from a Latent Class Analysis

Dechartres A. · Huas C. · Godart N. · Pousset M. · Pham A. · Divac S.M. · Rouillon F. · Falissard B.
aMaison des adolescents, PSIGIAM, U669, INSERM, bUMR S0669, Paris Sud and Paris Descartes University, cInstitut Mutualiste Montsouris, and dClinique des maladies mentales et de l’encéphale, Sainte Anne Hospital, Paris, and eDepartment of Public Health, Paul Brousse Hospital, APHP, Villejuif, France

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 10/15/2009
Accepted: 5/20/2010
Published online: 10/28/2010

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 2

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP

Abstract

Background/Aims: To empirically classify phenotypes of eating disorders (ED) using latent class analysis (LCA), and to validate this classification based on clinical outcomes. Methods: LCA was applied to 968 inpatients. The resultant classes were validated by clinical outcomes including mortality. Results: A 5-class solution showed the best fit. The symptoms of latent class 1 (LC1; 26% of the sample) resembled anorexia nervosa (AN), bingeing-purging (AN-B/P) subtype; those of LC2 (23%) resembled bulimia nervosa; those of LC3 (11%) were close to AN-B/P without weight and body concerns; those of LC4 resembled restrictive anorexia nervosa (RAN) without weight and body concerns, and those of LC5 RAN. A history of hospitalization for ED was significantly more frequent for LC3 and LC4. The lowest BMI at admission were presented in LC4. LC1 showed the highest level of psychological disturbances and LC4 the lowest. LC3 and LC4 differed from LC1 and LC5 by higher percentages of treatment dropout (64.9 vs. 57.2 and 55.7 vs. 47.5%, respectively; overall p = 0.001). Survival rates tended to be different between the LC (p = 0.09). Conclusions: Subgroups of AN patients with low weight and body concerns seem more severe at hospitalization and more difficult to manage, with a higher rate of treatment dropout than the ‘typical’ AN patients.


  

Author Contacts

Agnes Dechartres
INSERM, U669, PSIGIAM, Maison des adolescents
97 Boulevard de Port Royal
FR–75014 Paris (France)
Tel. +33 1 5841 2852, Fax +33 1 5841 2843, E-Mail adechartres@gmail.com

  

Article Information

Received: October 15, 2009
Accepted after revision: May 20, 2010
Published online: October 28, 2010
Number of Print Pages : 9
Number of Figures : 2, Number of Tables : 2, Number of References : 51

  

Publication Details

Psychopathology (International Journal of Descriptive and Experimental Psychopathology, Phenomenology and Psychiatric Diagnosis)

Vol. 44, No. 1, Year 2011 (Cover Date: January 2011)

Journal Editor: Mundt C. (Heidelberg), Akiskal H.S. (San Diego, Calif.), Mezzich J.E. (New York, N.Y.)
ISSN: 0254-4962 (Print), eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 10/15/2009
Accepted: 5/20/2010
Published online: 10/28/2010

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 2

ISSN: 0254-4962 (Print)
eISSN: 1423-033X (Online)

For additional information: http://www.karger.com/PSP


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