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Table of Contents
Vol. 4, No. 2, 2010
Issue release date: May – August
Section title: Published: July 2010

Open Access Gateway

Case Rep Gastroenterol 2010;4:243–249
(DOI:10.1159/000319013)

Primary Submucosal Squamous Cell Carcinoma of the Rectum Diagnosed by Endoscopic Ultrasound: Case Report and Literature Review

Al Hallak M.N.a–c · Hage-Nassar G.b · Mouchli A.b
aUniversity of North Dakota School of Medicine, bMeritCare Health System, and cRoger Maris Cancer Center, Fargo, N. Dak., USA
email Corresponding Author

M. Najeeb Al Hallak, MD

Department of Internal Medicine, MeritCare Hospital

801 Broadway, Fargo, ND 58122 (USA)

Tel. +1 701 261 2376, E-Mail alhallakmn@gmail.com

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Abstract

Primary colorectal squamous cell carcinoma (SCC) is one of the very rare malignancies of the gastrointestinal tract. The diagnosis cannot be made before ruling out other common primary sites. Using the endoscopic ultrasound (EUS) technique to get a tissue biopsy for submucosal tumors has not been demonstrated as the best diagnostic approach in the literature. Surgery is the gold standard treatment with arising evidence of good efficacy following conventional chemoradiation therapy. A 49-year-old male presented with rectal discomfort. Sigmoidoscopy revealed multiple submucosal masses in the rectosigmoid colon. Mucosal biopsies showed nonspecific inflammation. Subsequently, an EUS with fine needle biopsy was done and established the diagnosis of rectal SCC. There were no other primary sites noticed in the extensive evaluation. The patient chose to be treated only with chemoradiation without surgery. At the time of writing this report he had no evidence of recurrence achieving 2.5 years of survival. EUS is an emerging excellent approach to diagnose submucosal colorectal SCC. This case will add supportive evidence of having a complete response following combining treatment with squamous cell directed chemotherapy and external beam radiotherapy without preceded surgery.

© 2010 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Published: July 2010

Published online: July 24, 2010
Issue release date: May – August

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 0

ISSN: (Print)
eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG


Open Access License / Drug Dosage / Disclaimer

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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