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Table of Contents
Vol. 3, No. 1, 2011
Issue release date: December 2010
Section title: Short Communication
J Innate Immun 2011;3:65–70

Clotting Factors and Eicosanoids Protect against Nematode Infections

Hyrsl P.a, b · Dobes P.a, b · Wang Z.a · Hauling T.a · Wilhelmsson C.a · Theopold U.a
aDepartment of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden; bDepartment of Animal Physiology and Immunology, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic
email Corresponding Author

Dr. Ulrich Theopold

Department of Molecular Biology and Functional Genomics

University of Stockholm

SE–10691 Stockholm (Sweden)

Tel. +46 816 4181, Fax +46 816 6488, E-Mail uli@molbio.su.se

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We show that hemolymph clotting protects Drosophila melanogaster against infections with an entomopathogenic nematode and its symbiotic bacterium. We also provide biochemical and genetic evidence for an involvement of eicosanoids in the same infection model. Taken together, our results confirm the conserved nature of the immune function of clot formation.

© 2010 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Short Communication

Received: June 23, 2010
Accepted: August 18, 2010
Published online: October 16, 2010
Issue release date: December 2010

Number of Print Pages: 6
Number of Figures: 3
Number of Tables: 0

ISSN: 1662-811X (Print)
eISSN: 1662-8128 (Online)

For additional information: http://www.karger.com/JIN

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