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Vol. 80, No. 3, 2011
Issue release date: April 2011
Section title: Regular Article
Psychother Psychosom 2011;80:144–150
(DOI:10.1159/000320738)

A Randomized Controlled Trial of Cognitive Behavioral Group Therapy for Bipolar Disorder

Gomes B.C. · Abreu L.N. · Brietzke E. · Caetano S.C. · Kleinman A. · Nery F.G. · Lafer B.
Bipolar Disorders Research Program, Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil

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Article / Publication Details

First-Page Preview
Abstract of Regular Article

Received: 5/6/2010
Accepted: 8/26/2010
Published online: 3/3/2011

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 1

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS

Abstract

Background: This study evaluated the effectiveness of adjunctive cognitive behavioral group therapy (CBGT) to prevent recurrence of episodes in euthymic patients with bipolar disorder. Methods: A randomized controlled single-blind trial was conducted with 50 patients with bipolar disorder types I and II followed up for at least 12 months in an outpatient service and whose disease was in remission. An experimental CBGT manual was developed and added to treatment as usual (TAU), and results were compared with TAU alone. Results: Intention-to-treat analysis showed that there was no difference between groups in terms of time until any relapse (Wilcoxon = 0.667; p = 0.414). When considering type of relapse, there was still no difference in either depressive (Wilcoxon = 3.328; p = 0.068) or manic episodes (Wilcoxon = 1.498; p = 0.221). Although occurrence of episodes also did not differ between groups (χ2 = 0.28; p = 0.59), median time to relapse was longer for patients treated with CBGT compared to TAU (Mann-Whitney = –2.554; p = 0.011). Conclusions: Time to recurrence and number of episodes were not different in the group of patients treated with CBGT. However, median time to relapse was shorter in the TAU group. Studies with larger samples may help to clarify whether our CBGT approach prevents new episodes of bipolar disorder. Our findings also indicated that CBGT is feasible in euthymic patients with bipolar disorder and should be investigated in future studies. To our knowledge, this is the first publication of a controlled trial of CBGT for euthymic patients with bipolar disorder.


  

Author Contacts

B.C. Gomes
Programa de Transtorno Bipolar (PROMAN), Instituto de Psiquiatria
Hospital das Clinicas, Faculdade de Medicina da Universidade de São Paulo
Rua Dr. Ovídio Pires de Campos 785, 3° andar, São Paulo 05403-010 (Brazil)
Tel./Fax +55 11 3069 6928, E-Mail bernardocarramao@gmail.com

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Article Information

Received: May 6, 2010
Accepted after revision: August 26, 2010
Published online: March 3, 2011
Number of Print Pages : 7
Number of Figures : 2, Number of Tables : 1, Number of References : 40

  

Publication Details

Psychotherapy and Psychosomatics

Vol. 80, No. 3, Year 2011 (Cover Date: April 2011)

Journal Editor: Fava G.A. (Bologna)
ISSN: 0033-3190 (Print), eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS


Article / Publication Details

First-Page Preview
Abstract of Regular Article

Received: 5/6/2010
Accepted: 8/26/2010
Published online: 3/3/2011

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 1

ISSN: 0033-3190 (Print)
eISSN: 1423-0348 (Online)

For additional information: http://www.karger.com/PPS


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