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Vol. 17, No. 5, 2010
Issue release date: October 2010
Forsch Komplementmed 2010;17:250–257
Original Article · Originalarbeit

Effects of Homeopathic Medicines on Mood of Adults with Histories of Coffee-Related Insomnia

Brooks A.J.a · Bell I.R.a,b,c,d · Howerter A.b,e · Jackson N.b,d · Aickin M.b
a Department of Psychology, the University of Arizona, b Department of Family and Community Medicine, the University of Arizona College of Medicine, c Department of Psychiatry, the University of Arizona College of Medicine, d Mel and Enid Zuckerman College of Public Health, the University of Arizona, e Division of Family Studies and Human Development, the University of Arizona, Tucson, AZ USA


Background/Aims: The purpose of this within-subjects feasibility study was to determine whether two different homeopathic remedies, Nux Vomica (NV) and Coffea Cruda (CC), exert effects on subjective mood ratings in healthy adults with a history of coffee-induced insomnia. The impact of individual personality traits, anxiety sensitivity or Type A cynical hostility, and homeopathic constitutional type (HTYPE-NV, HTYPE-CC), on remedy effects was examined to evaluate differential responsivity, in accord with clinical claims. Subjects and Methods: Young adults of both sexes (ages 18–31) with above-average scores on standardized personality scales for either cynical hostility or anxiety sensitivity, and a history of coffee-induced insomnia, participated in the month-long study. At-home polysomnographic recordings were obtained on successive pairs of nights once per week for a total of 8 recordings (nights 1, 2, 8, 9, 15, 16, 22, 23). Subjects (N = 59) received placebo pellets on night 8 (single-blind) and verum pellets in 30c doses of one of two homeopathic remedies, NV or CC, on night 22 (doubleblind). Subjects completed the Profile of Mood States Scales at bedtime. Results: The remedies produced differential effects on anger and overall mood, with improved mood following CC administration. A similar trend for depression was observed. Anxiety sensitive subjects experienced less tension following CC, whereas hostile subjects receiving CC became more tense. The high HTYPE-CC receiving CC experienced less vigor. The high HTYPE-CC receiving NV experienced more vigor.

 goto top of outline Author Contacts

Audrey J. Brooks, PhD, Department of Psychology, University of Arizona, PO Box 210068, Tucson, AZ 85721, USA, Tel. +1 520 6269500, Fax 6218421,

 goto top of outline Article Information

Published online: October 1, 2010
Number of Print Pages : 8

 goto top of outline Publication Details

Forschende Komplementärmedizin / Research in Complementary Medicine (Research Practice Perspectives - Wissenschaft Praxis Perspektiven)

Vol. 17, No. 5, Year 2010 (Cover Date: October 2010)

Journal Editor: Walach H. (Frankfurt/O.)
ISSN: 1661-4119 (Print), eISSN: 1661-4127 (Online)

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