Giant Basal Cell Carcinoma of the Breast Mimicking Paget’s Disease: Complete Remission after Photodynamic TherapyMikhaimer N.C. · Kähler K.C. · Schwarz T. · Mundhenke C. · Hauschild A.
aKlinik für Dermatologie, Venerologie und Allergologie, bKlinik für Gynäkologie und Geburtshilfe, Mammazentrum, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Kiel, Germany
Background: Basal cell carcinoma (BCC) in the nipple area is extremely rare and can be mistaken for Paget’s disease. Case Report: A 47-year-old woman complained of a slowly growing, scaly erythematous plaque around her right nipple which had developed over several years. Paget’s disease of the breast was suspected. Biopsies revealed a superficial BCC. The maximum tumor thickness was measured as 1 mm. Considering the superficial character of the tumor, photodynamic therapy (PDT) as a non-invasive approach was performed. Complete remission (CR) with an excellent cosmetic result was achieved after 4 PDT sessions. In the follow-up, CR with no signs of a local recurrence was evident after more than 24 months. Conclusion: In similar superficial cases of BCCs, non-invasive procedures such as PDT can be discussed as an alternative option to radical surgery or radiotherapy, with an excellent aesthetic outcome in carefully selected cases.
Dr. med. Nadia C. Mikhaimer, Klinik für Dermatologie, Venerologie und Allergologie, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Schittenhelmstr. 7, 24105 Kiel, Germany, Tel. +49 431 597-1512, Fax -1853, NMikhaimer@dermatology.uni-kiel.de
Published online: October 15, 2010
Number of Print Pages : 3
Onkologie (International Journal for Cancer Research and Treatment)
Vol. 33, No. 11, Year 2010 (Cover Date: October 2010)
Journal Editor: Schmoll H.-J. (Halle/Saale)
ISSN: 0378-584X (Print), eISSN: 1423-0240 (Online)
For additional information: http://www.karger.com/ONK