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Vol. 221, No. 4, 2010
Issue release date: December 2010
Section title: Case and Review
Dermatology 2010;221:296–299
(DOI:10.1159/000321191)

Lichen Planus Occurring after Influenza Vaccination: Report of Three Cases and Review of the Literature

Sato N.A. · Kano Y. · Shiohara T.
Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan

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Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 7/30/2010
Accepted: 6/9/2010
Published online: 11/3/2010

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Although influenza vaccine is thought to be effective and safe, it occasionally causes systemic reactions such as toxic epidermal necrolysis, bullous pemphigoid, lichen planus (LP), etc. The period of increased risk of developing these events was different depending on the immune responses induced by the vaccination. We report 3 cases of LP which appeared after an influenza vaccination. Our cases indicate that the period of increased risk of developing vaccine-related LP was concentrated within 2 weeks after vaccination, and that the vaccine alone represents a triggering factor necessary for immune alteration sufficient for the development of LP. Because these adverse events tend to develop over a predictable time course, the time of onset may give an important clue to the diagnosis of vaccine-related diseases. We suggest that a history of recent vaccination should be sought in all patients presenting with linear LP.


  

Author Contacts

Noriko Aota Sato, MD
Department of Dermatology
Kyorin University School of Medicine
6-20-2 Shinkawa Mitaka, Tokyo 181-8611 (Japan)
Tel. +81 422 475 511, Fax +81 422 479 632, E-Mail nrkcc0605-ao@ks.kyorin-u.ac.jp

  

Article Information

Received: July 30, 2010
Accepted after revision: September 6, 2010
Published online: November 3, 2010
Number of Print Pages : 4
Number of Figures : 3, Number of Tables : 0, Number of References : 17

  

Publication Details

Dermatology

Vol. 221, No. 4, Year 2010 (Cover Date: December 2010)

Journal Editor: Saurat J.-H. (Geneva)
ISSN: 1018-8665 (Print), eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 7/30/2010
Accepted: 6/9/2010
Published online: 11/3/2010

Number of Print Pages: 4
Number of Figures: 3
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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