Dermoscopy of Pigmented Lesions of the Vulva: A Retrospective Morphological StudyFerrari A. · Zalaudek I. · Argenziano G. · Buccini P. · De Simone P. · Silipo V. · Eibenschutz L. · Mariani G. · Covello R. · Sperduti I. · Mariani L. · Catricalà C.
aDepartment of Oncologic Dermatology, Santa Maria and San Gallicano Institute of Rome, bDepartment of Pathology, cUnit of Biostatistics and dDepartment of Oncologic Gynecology, Regina Elena National Cancer Institute of Rome, Rome, and eDepartment of Dermatology, Second University of Naples, Naples, Italy; fDepartment of Dermatology, Medical University of Graz, Graz, Austria
Background: The dermoscopic patterns of pigmented skin tumors are influenced by the body site. Objective: To evaluate the clinical and dermoscopic features associated with pigmented vulvar lesions. Methods: Retrospective analysis of clinical and dermoscopic images of vulvar lesions. The χ2 test was used to test the association between clinical data and histopathological diagnosis. Results: A total of 42 (32.8%) melanocytic and 86 (67.2%) nonmelanocytic vulvar lesions were analyzed. Nevi significantly prevailed in younger women compared with melanomas and melanosis and exhibited most commonly a globular/cobblestone (51.3%) and a mixed (21.6%) pattern. Dermoscopically all melanomas showed a multicomponent pattern. Melanotic macules showed clinical overlapping features with melanoma, but their dermoscopic patterns differed significantly from those observed in melanomas. Conclusion: The diagnosis and management of pigmented vulvar lesions should be based on a good clinicodermoscopic correlation. Dermoscopy may be helpful in the differentiation of solitary melanotic macules from early melanoma.
Iris Zalaudek, MD
Department of Dermatology, Medical University of Graz
AT–8036 Graz (Austria)
Tel. +43 676 332 8269, Fax +43 316 385 2466, E-Mail email@example.com
Received: November 1, 2010
Accepted: December 1, 2010
Published online: February 9, 2011
Number of Print Pages : 10
Number of Figures : 4, Number of Tables : 3, Number of References : 28
Vol. 222, No. 2, Year 2011 (Cover Date: May 2011)
Journal Editor: Saurat J.-H. (Geneva)
ISSN: 1018-8665 (Print), eISSN: 1421-9832 (Online)
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