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Table of Contents
Vol. 86, No. 3, 2011
Issue release date: April 2011
Section title: Original Paper
Urol Int 2011;86:315–319
(DOI:10.1159/000323836)

Lidocaine Suppository for Transrectal Ultrasound-Guided Biopsy of the Prostate: A Prospective, Double-Blind, Randomized Study

Goluza E.a · Hudolin T.b · Kastelan Z.b · Peric M.a · Murselovic T.a · Sosic H.b
aDepartment of Anesthesiology, Reanimatology and Intensive Care and bDepartment of Urology, KBC Zagreb, Zagreb, Croatia

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: July 20, 2010
Accepted: July 12, 2010
Published online: February 19, 2011
Issue release date: April 2011

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 1

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: http://www.karger.com/UIN

Abstract

Aims: To investigate analgesia using lidocaine suppositories for prostate biopsy. Methods: From 2007 to 2009, 160 patients underwent transrectal ultrasound-guided prostate biopsy at the Department of Urology, KBC Zagreb. 80 patients received a 60-mg lidocaine suppository intrarectally at different time points from 15 to 120 min before biopsy and 80 patients received a glycerin suppository as placebo. The pain level was evaluated using a visual analogue scale (VAS). Results: There were no statistically significant differences between the groups, i.e. they were similar regarding patients’ age, prostate-specific antigen levels, prostate volume and the incidence of diagnosis of malignancy on biopsy. The mean pain score in the lidocaine group (3 ± 1) was significantly lower than the mean pain score in the glycerin group (4.1 ± 1.3) (p < 0.001). A noticeable trend towards lower pain scores in the lidocaine group was observed with more time elapsing from placing the suppository till the biopsy and the optimal time for performing biopsy starting approximately 1 h after placing the suppository. Conclusions: Lidocaine suppositories are an easy-to-use, self-applicable (by the patient) and cheap method of local analgesia, with acceptable results. Possible complications related to this procedure are insignificant.

© 2011 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: July 20, 2010
Accepted: July 12, 2010
Published online: February 19, 2011
Issue release date: April 2011

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 1

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: http://www.karger.com/UIN


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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