Cover

Pediatric and Adolescent Gynecology

Evidence-Based Clinical Practice

Editor(s): Sultan C. (Montpellier) 
Table of Contents
Vol. 22, 2012
Section title: The Prepubertal Girl
Sultan C (ed): Pediatric and Adolescent Gynecology. Evidence-Based Clinical Practice. 2nd, revised and extended edition. Endocr Dev. Basel, Karger, 2012, vol 22, pp 56–71
(DOI:10.1159/000326631)

Disorders of Sex Development: Neonatal Diagnosis and Management

Paris F. · Gaspari L. · Philibert P. · Maïmoun L. · Kalfa N. · Sultan C.
aUnité d’Endocrinologie-Gynécologie Pédiatriques, Département de Pédiatrie, Hôpital A. de Villeneuve, bService d’Hormonologie (Développement et Reproduction), Hôpital Lapeyronie, et cService de Chirurgie Pédiatrique, Hôpital Lapeyronie, CHU Montpellier et Université Montpellier 1, Montpellier, France

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Article / Publication Details

First-Page Preview
Abstract of The Prepubertal Girl

Published online: 7/25/2012
Cover Date: 2012

Number of Print Pages: 16
Number of Figures: 3
Number of Tables: 2

ISBN: 978-3-8055-9336-6 (Print)
eISBN: 978-3-8055-9337-3 (Online)

Abstract

The disorders of sex development (DSD) refer to the insufficient virilization of the external genitalia of a 46,XY fetus or the excessive virilization of those of the 46,XX fetus. Some of these disorders are associated with karyotype abnormalities. DSD arise from abnormal gonadal determination or sex differentiation, as in the case of the abnormal testosterone synthesis or androgen insensitivity of 46,XY DSD. The impact of environmental endocrine disrupting chemicals during fetal life requires further investigation. The basic investigations should include SRY gene sequencing and measurement of 17-hydroxyprogesterone, anti-Mullerian hormone, and testosterone. Choosing the sex of rearing is difficult and the decision must be made by an experienced multidisciplinary team.


  

Author Contacts

Prof. Charles Sultan, MD, PhD, Unité d’Endocrinologie-Gynécologie Pédiatriques, Département de Pédiatrie, Hôpital A. de Villeneuve, FR–34295 Montpellier cedex 5 (France), Tel. +33 467 33 86 96, E-Mail c-sultan@chu-montpellier.fr

  

Article Information

Published online: July 25, 2012
Number of Print Pages : 16

  

Publication Details

Book Serie: Endocrine Development, Vol. 22, Year 2012

Editor(s): Mullis, P.-E. (Bern)
ISSN: 1421-7082 (Print), eISSN: 1662-2979 (Online)

For additional information:
http://content.karger.com/ProdukteDB/produkte.asp?issn=1421-7082

Book Title: Pediatric and Adolescent Gynecology (Evidence-Based Clinical Practice)

Editor(s): Sultan C (ed)

For additional information:
http://content.karger.com/ProdukteDB/produkte.asp?issn=1421-7082&volume=22


Article / Publication Details

First-Page Preview
Abstract of The Prepubertal Girl

Published online: 7/25/2012
Cover Date: 2012

Number of Print Pages: 16
Number of Figures: 3
Number of Tables: 2

ISBN: 978-3-8055-9336-6 (Print)
eISBN: 978-3-8055-9337-3 (Online)


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