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Vol. 65, No. 5, 2011
Issue release date: May 2011
Section title: Original Paper
Eur Neurol 2011;65:302–306
(DOI:10.1159/000327315)

Restless Legs Syndrome in Multiple Sclerosis

Aydar G. · Kurt S. · Karaer Unaldi H. · Erkorkmaz U.
Departments of aNeurology and bBiostatistics, Gaziosmanpasa University Medical Faculty, Tokat, Turkey

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 10/28/2010
Accepted: 3/14/2011
Published online: 5/13/2011

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 2

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE

Abstract

Aims: Multiple sclerosis (MS) is a demyelinating neurodegenerative inflammatory autoimmune disease. Restless legs syndrome (RLS) is characterized as a strong urge to move the legs to stop abnormal sensations there. In this study, we aimed to investigate whether or not the increased RLS frequency seen in MS could be associated with depression and fatigue. Methods: The study involved 98 patients with definite MS and 129 healthy volunteers. The Beck Depression Inventory and Fatigue Severity Scale were used to assess all participants. The patients and the healthy volunteers were examined for RLS according to the criteria of the International Restless Legs Syndrome Study Group. Results: When the factors related to RLS in MS were evaluated, there were significant relationships found among age, type of MS, pyramidal symptoms, intestinal and bladder symptoms, number of lesions in MR, depression, and fatigue. Risk factors for RLS were also seen more frequently in the MS group than in the healthy volunteers. Conclusion: RLS was seen 2.55 times more frequently in patients with MS than in the control group. This was due to the existence of numerous factors rather than a single factor – including depression and fatigue.


  

Author Contacts

Semiha Kurt, MD
Department of Neurology
Gaziosmanpasa University Faculty of Medicine
TR–60100 Tokat (Turkey)
Tel. +90 356 212 5746/1062, E-Mail gsemihakurt@hotmail.com

  

Article Information

Received: October 28, 2010
Accepted: March 14, 2011
Published online: May 13, 2011
Number of Print Pages : 5
Number of Figures : 0, Number of Tables : 2, Number of References : 23

  

Publication Details

European Neurology

Vol. 65, No. 5, Year 2011 (Cover Date: May 2011)

Journal Editor: Bogousslavsky J. (Montreux)
ISSN: 0014-3022 (Print), eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 10/28/2010
Accepted: 3/14/2011
Published online: 5/13/2011

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 2

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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