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Table of Contents
Vol. 64, No. 3, 2011
Issue release date: July 2011
Section title: Review
Free Access
Neuropsychobiology 2011;64:129–140

Continuation and Maintenance Electroconvulsive Therapy for Mood Disorders: Review of the Literature

Petrides G.a · Tobias K.G.b · Kellner C.H.b · Rudorfer M.V.c
aThe Zucker Hillside Hospital, North Shore-LIJ Health System, Glen Oaks, N.Y., bThe Mount Sinai School of Medicine, New York, N.Y., and cNational Institute of Mental Health, Bethesda, Md., USA
email Corresponding Author

Georgios Petrides, MD

The Zucker Hillside Hospital

Research Division

7559 263rd street, Glen Oaks, NY 11004 (USA)

Tel. +1 718 470 8569, E-Mail petrides@lij.edu

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Background: Electroconvulsive therapy (ECT) is a highly effective treatment for mood disorders. Continuation ECT (C-ECT) and maintenance ECT (M-ECT) are required for many patients suffering from severe and recurrent forms of mood disorders. This is a review of the literature regarding C- and M-ECT. Methods: We conducted a computerized search using the words continuation ECT, maintenance ECT, depression, mania, bipolar disorder and mood disorders. We report on all articles published in the English language from 1998 to 2009. Results: We identified 32 reports. There were 24 case reports and retrospective reviews on 284 patients. Two of these reports included comparison groups, and 1 had a prospective follow-up in a subset of subjects. There were 6 prospective naturalistic studies and 2 randomized controlled trials. Conclusions: C-ECT and M-ECT are valuable treatment modalities to prevent relapse and recurrence of mood disorders in patients who have responded to an index course of ECT. C-ECT and M-ECT are underused and insufficiently studied despite positive clinical experience of more than 70 years. Studies which are currently under way should allow more definitive recommendations regarding the choice, frequency and duration of C-ECT and M-ECT following acute ECT.

© 2011 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Review

Received: November 19, 2009
Accepted: June 19, 2010
Published online: July 29, 2011
Issue release date: July 2011

Number of Print Pages: 12
Number of Figures: 0
Number of Tables: 2

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: http://www.karger.com/NPS

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