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Vol. 3, No. 2, 2011
Issue release date: May – August
Section title: Published: May 2011

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Case Rep Dermatol 2011;3:118–123
(DOI:10.1159/000328999)

Postsurgical Paracicatricial Cutaneous Satellitosis of Giant Cell Tumour of the Tendon Sheath, Localized Type

Caputo V. · Fiorella S. · Orlando E.
Departments of aDermatology and bHuman Pathology, University of Palermo, Palermo, Italy

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Abstract

Tenosynovial giant cell tumour (localized type) is a tumour of tendon sheaths and interphalangeal joints, affecting the digits and arising from the synovium. It is characterized by a proliferation of mononuclear cells and osteoclast-like polykaryocytes. Its propagation to the skin is an exceptional event, which can take place either in localized form in the fingertips (localized type) or in the rare diffuse form called giant cell tumour of the tendon sheath (diffuse type). We report here a case of giant cell tumour with cutaneous satellites, which appeared close to and around the surgical scar following the excision of the primary lesion, in a 9-year-old boy. In the cutaneous satellites, a few signs of transformation could be observed, consisting of the lack of stroma and pronounced cellularity characterized by sheets of rounded synovial-like cells admixed with multinucleated giant cells and xanthoma cells. No relapse was observed 1 year after a plastic surgery procedure (complete replacement of the involved skin). Diffuse lesions usually represent a diagnostic problem in comparison with their localized counterparts. The malignant transformation of an originally typical tenosynovial giant cell tumour is a rare but well-documented event. Our case seems to represent a typical example because the pronounced cellularity might wrongly lead to a diagnosis of malignancy.


  

Author Contacts

Dr. Valentina Caputo
Viale Strasburgo, 440IT–90146 Palermo (Italy)
Tel. +39 0916 890 680E-Mail fiorellasanti@tim.it

  

Article Information

Published online: May 27, 2011
Number of Print Pages : 6
Number of Figures : 4,

  

Publication Details

Case Reports in Dermatology

Vol. 3, No. 2, Year 2011 (Cover Date: May - August)

Journal Editor: Jemec G. (Roskilde)
ISSN: NIL (Print), eISSN: 1662-6567 (Online)

For additional information: http://www.karger.com/CDE


Article / Publication Details

First-Page Preview
Abstract of Published: May 2011

Published online: 5/27/2011

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: (Print)
eISSN: 1662-6567 (Online)

For additional information: http://www.karger.com/CDE


Open Access License / Drug Dosage

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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