Cover

Controversies in Acute Kidney Injury

Editor(s): Kellum J.A. (Pittsburgh, Pa.) 
Ronco C. (Vicenza) 
Vincent J.-L. (Brussels) 
Table of Contents
Vol. 174, 2011
Section title: Prevention/Treatment/Rehabilitation: What’s on the Horizon?
Kellum JA, Ronco C, Vincent J-L (eds): Controversies in Acute Kidney Injury. Contrib Nephrol. Basel, Karger, 2011, vol 174, pp 163–172
(DOI:10.1159/000329394)

Acute Kidney Injury in Children: Prevention, Treatment and Rehabilitation

Goldstein S.L.
University of Cincinnati College of Medicine, Director, Center for Acute Care Nephrology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

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Article / Publication Details

First-Page Preview
Abstract of Prevention/Treatment/Rehabilitation: What’s on the Horizon?

Published online: 9/9/2011
Cover Date: 2011

Number of Print Pages: 10
Number of Figures: 1
Number of Tables: 1

ISBN: 978-3-8055-9810-1 (Print)
eISBN: 978-3-8055-9811-8 (Online)

Abstract

Pediatric acute kidney injury (AKI) epidemiology has shifted from primary kidney disease to secondary to another organ system illness or its treatment with nephrotoxic medications. Similar to adult patients, critically ill children with AKI with multiorgan failure exhibit high mortality rates, yet conducting interventional trials to prevent, treat or mitigate the effects of AKI in children have been hampered by relatively low event rates and the reliance on serum creatinine as the biomarker of AKI. However, recent advancements in standardizing the AKI definition via the pediatric modified RIFLE criteria, multicenter collaboration via the Prospective Pediatric CRRT Registry Group and multiple validation studies of novel AKI biomarkers in children have provided the essential components to evaluate preventive and therapeutic strategies to attack pediatric AKI as a disease state. The scope of this article is to review the advancements in the study of pediatric AKI over the past decade and offer a compelling and bright view of what is on the horizon for the prevention, treatment and rehabilitation of AKI in kids.


  

Author Contacts

Stuart L. Goldstein, MD, Professor of Pediatrics, Cincinnati Children’s Hospital Medical Center, Center for Acute Care Nephrology, 3333 Burnet Avenue, Cincinnati, OH 45229 (USA), Tel. +1 513 803 3295, E-Mail stuart.goldstein@cchmc.org

  

Article Information

Published online: September 09, 2011
Number of Print Pages : 10

  

Publication Details

Book Serie: Contributions to Nephrology, Vol. 174, Year 2011

Editor(s): Ronco, C. (Vicenza)
ISSN: 0302-5144 (Print), eISSN: 1662-2782 (Online)

For additional information:
http://content.karger.com/ProdukteDB/produkte.asp?issn=0302-5144

Book Title: Controversies in Acute Kidney Injury

Editor(s): Kellum JA, Ronco C, Vincent J-L (eds)

For additional information:
http://content.karger.com/ProdukteDB/produkte.asp?issn=0302-5144&volume=174


Article / Publication Details

First-Page Preview
Abstract of Prevention/Treatment/Rehabilitation: What’s on the Horizon?

Published online: 9/9/2011
Cover Date: 2011

Number of Print Pages: 10
Number of Figures: 1
Number of Tables: 1

ISBN: 978-3-8055-9810-1 (Print)
eISBN: 978-3-8055-9811-8 (Online)


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