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Vol. 5, No. 2, 2011
Issue release date: May – August
Section title: Published: July 2011

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Case Rep Gastroenterol 2011;5:416–421
(DOI:10.1159/000330480)

Metastatic Kaposi’s Sarcoma with Perirectal Involvement Diagnosed with Endoscopic Ultrasound-Guided EchoBrush Cytology Sampling

Cornett D. · Benson M. · Attia S. · Weiss J. · Gopal D.
aDivision of Gastroenterology and Hepatology and bDivision of Medical Oncology, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, Wisc., USA

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Abstract

AIDS-related Kaposi’s sarcoma (KS) is a low-grade vascular tumor that occurs in association with human herpesvirus 8 infection. Here we report the case of a 21-year-old male with recently diagnosed cutaneous KS who presented with rectal bleeding and anal pruritus. Initial endoscopic evaluation was nondiagnostic. CT imaging showed diffuse lymphadenopathy including perirectal involvement which was suspicious for metastatic KS. Echoendoscopy with needle biopsies and EchoBrush sampling of the lymph nodes revealed spindle cells confirming metastatic KS. Treatment was initiated with liposomal doxorubicin resulting in rapid improvement of the skin lesions. After treatment completion, repeat CT imaging showed improved lymphadenopathy. No further rectal bleeding or perianal pruritus was reported. Although the EchoBrush has previously been used to aid in the diagnosis of pancreatic lesions, this report describes a novel use of EchoBrush to diagnose KS from perirectal lymph nodes.


  

Author Contacts

Deepak Gopal, MD, FRCP(C)
Division of Gastroenterology and Hepatology, University of Wisconsin Medical School4229 Medical Foundation Centennial Building, 1685 Highland Ave
Madison, WI 53705 (USA)
Tel. +1 608 263 7322, E-Mail dvg@medicine.wisc.edu

  

Article Information

Published online: July 22, 2011
Number of Print Pages : 6
Number of Figures : 4,

  

Publication Details

Case Reports in Gastroenterology

Vol. 5, No. 2, Year 2011 (Cover Date: May - August)

Journal Editor: Urrutia R. (Rochester, Minn.), Lomberk G. (Rochester, Minn.)
ISSN: NIL (Print), eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG


Article / Publication Details

First-Page Preview
Abstract of Published: July 2011

Published online: 7/22/2011

Number of Print Pages: 6
Number of Figures: 4
Number of Tables: 0

ISSN: (Print)
eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG


Open Access License / Drug Dosage

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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