Melamine-Related Urinary Stones in 195 Infants and Young Children: Clinical Features within 2 Years of Follow-UpWen J.G. · Chang Q.L. · Lou A.F. · Li Z.Z. · Lu S. · Wang Y. · Wang Y.L. · Hu J.H. · Mao S.P. · Zhang Y. · Xue R. · Ren C. · Xing L. · Zhang G.X. · Zhang S. · Djurhuus J.C. · Frøkiaer J.
aUrodynamic Center, Department of Urology of the First Affiliated Hospital of Zhengzhou University, Institute of Clinical Medicine of Zhengzhou University, Zhengzhou, China; bInstitute of Clinical Medicine, University of Aarhus, Aarhus, Denmark
Objective: To summarize the clinical features and follow-up, the effects of melamine-tainted milk powder (MMP) consumption on kidney and body growth in children who suffered from melamine-related urinary stones (MUS) 2 years earlier were checked. Measurements: Body height and weight, kidney and bladder morphology monitored by ultrasound, urinalysis and renal function were recorded. Plain abdominal radiography was performed for differential diagnosis. The first follow-up was carried out at 15 months and the second 2 years later for patients who showed any abnormality at the first follow-up. Two hundred age- and gender-matched cohorts were included. Results: All cases received conservative treatment in hospital. Fifteen months of follow-up was successfully carried out in 167 cases. 91 children had residual MUS at the time of discharge, 58 MUS disappeared completely, 25 dissolved partially, 1 increased in size, and 7 did not change. At 2 years of follow-up, the residual stones all disappeared except for 1 case; the patient who showed a delayed development with regard to height caught up at 24 months of follow-up. Conclusions: Conservative treatment shows a high effectiveness in cases with residual MUS. Consumption of MMP with timely treatment did not demonstrate an evident impact on kidney and bladder although body height is slightly affected in a few cases.
Jian Guo Wen
Urodynamic Center, Department of Urology of First Affiliated Hospital of Zhengzhou University and Institute of Clinical Medicine of Zhengzhou University
No. 1, Jian She East Road, Zhengzhou, 450052 (China)
Received: March 4, 2011
Accepted after revision: June 10, 2011
Published online: November 1, 2011
Number of Print Pages : 5
Number of Figures : 1, Number of Tables : 1, Number of References : 16
Vol. 87, No. 4, Year 2011 (Cover Date: December 2011)
Journal Editor: Wirth M.P. (Dresden), Porena M. (Perugia), Hakenberg O.W. (Rostock), Castro-Diaz D. (Santa Cruz de Tenerife)
ISSN: 0042-1138 (Print), eISSN: 1423-0399 (Online)
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