Living Donor Liver Transplantation for Hepatocellular Carcinoma: The Japanese ExperienceTamura S. · Sugawara Y. · Kokudo N.
Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, and Organ Transplantation Service, University of Tokyo, Tokyo, Japan
Treatment strategies against hepatocellular carcinoma have progressed remarkably over the past decade. In Asia, evidence-based guidelines for the management of hepatocellular carcinoma have evolved, including the option of liver transplantation. Due to severe organ shortage, however, living donor liver transplantation has become mainstream in Japan. Unlike deceased donor transplantation, living donor transplantation is not limited by the restrictions imposed by the nationwide allocation system. The decision for transplantation often depends on institutional or case-by-case considerations, balancing the will of the donor, the operative risk, and the overall survival benefit for the recipient. Cumulative data from the national multicenter registry analysis as well as individual center experience suggest that expansion of the Milan criteria is warranted.
Norihiro Kokudo, Artificial Organ and Transplantation Division
Hepato-Biliary and Pancreatic Surgery Division, Department of Surgery
Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo
Bunkyo-ku, Tokyo 113-8655 (Japan)
Tel. +81 3 3815 5411, E-Mail KOKUDO-2SU@h.u-tokyo.ac.jp
Published online: December 22, 2011
Number of Print Pages : 5
Number of Figures : 1, Number of Tables : 1, Number of References : 45
Oncology (International Journal for Cancer Research and Treatment)
Vol. 81, No. Suppl. 1, Year 2011 (Cover Date: December 2011)
Journal Editor: Markman M. (Philadelphia, Pa.)
ISSN: 0030-2414 (Print), eISSN: 1423-0232 (Online)
For additional information: http://www.karger.com/OCL