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Vol. 18, No. 5, 2011
Issue release date: Oktober 2011
Forsch Komplementmed 2011;18:264–268
Original Article · Originalarbeit

Effectiveness of a Herbal Formula in Women with Menopausal Syndrome

Yakoot M.a · Salem A.b · Omar A.-M.c
a Green Clinics, b Alexandria Helmy Polyclinic, c Faculty of Pharmacy, Alexandria University, Alexandria, Egypt


Background: Lady 4 is a combination of 4 natural components (evening primrose oil, damiana, ginseng, royal jelly) with a known history of traditional use for menopausal symptoms. Objective: To study efficacy and safety of Lady 4 in women suffering from menopausal syndrome. Methods: 120 women with menopausal symptoms were randomised into an experimental group treated with 2 capsules of Lady 4 daily and a control group treated with placebo. The outcome was measured by the Menopause Rating Scale II (MRS-II). Results: There was a statistically significant improvement in the MRS-II score in both groups after 2 and 4 weeks of treatment, but the improvement was significantly better in the Lady 4 group (p < 0.001). 86.7% in the Lady 4 group and 56.7% in the placebo group rated the therapy success as ‘much improved’ or ‘very much improved’. Conclusion: Lady 4 may be beneficial in the treatment of menopausal syndrome and can be used as a safe natural promoter of health and well-being in women during the menopausal transition.

 goto top of outline Author Contacts

Mostafa Yakoot, M.D., Green Clinics and Research Center, 27 Green Street, 21121 Alexandria, Egypt, Tel. +20 123 927 561,

 goto top of outline Article Information

Published online: October 10, 2011
Number of Print Pages : 5

 goto top of outline Publication Details

Forschende Komplementärmedizin / Research in Complementary Medicine (Research Practice Perspectives - Wissenschaft Praxis Perspektiven)

Vol. 18, No. 5, Year 2011 (Cover Date: Oktober 2011)

Journal Editor: Walach H. (Frankfurt/O.)
ISSN: 1661-4119 (Print), eISSN: 1661-4127 (Online)

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