Journal Mobile Options
Table of Contents
Vol. 4, No. 3, 2011
Issue release date: September – December
Section title: Published: November 2011

Open Access Gateway

Case Rep Oncol 2011;4:547–554
(DOI:10.1159/000334745)

Aleukemic Leukemia Cutis Manifesting with Disseminated Nodular Eruptions and a Plaque Preceding Acute Monocytic Leukemia: A Case Report

Yonal I. · Hindilerden F. · Coskun R. · Dogan O.I. · Nalcaci M.
aDivision of Hematology, Department of Internal Medicine, and bDepartment of Pathology, Medical Faculty, Istanbul University, and cDivision of Hematology, Department of Internal Medicine, Istanbul Bilim University, Istanbul, Turkey

Do you have an account?

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

Abstract

Aleukemic leukemia cutis (ALC), a discrete tumor of leukemic cells involving the skin, may be the first manifestation of acute myeloid leukemia, preceding the onset in marrow and blood by months and years. ALC is often difficult to diagnose and is associated with a dismal prognosis. A 63-year-old male presented with nodular swellings on the face, a plaque extending over the right shoulder and multiple enlarged cervical lymph nodes. The skin biopsy of the plaque lesion showed a diffuse neoplastic infiltration extending from the dermis to subcutaneous tissue with diffuse positivity for myeloperoxidase and focal positivity for CD34 on immunohistochemical staining. The diagnosis was leukemia cutis. One month later, acute monocytic leukemia (FAB AML-M5b) was diagnosed. The patient died on the seventh month of diagnosis.


  

Author Contacts

Yonal Ipek
İstanbul Üniversitesi İstanbul Tıp Fakültesi İç Hastalıkları ABD
Hematoloji BD, TR–34104 Fatih, Istanbul (Turkey)
Tel. +90 535 687 59 92, E-Mail ipekyonal@yahoo.com.tr

  

Article Information

Published online: November 22, 2011
Number of Print Pages : 8
Number of Figures : 4,

  

Publication Details

Case Reports in Oncology

Vol. 4, No. 3, Year 2011 (Cover Date: September - December)

Journal Editor: Markman M. (Philadelphia, Pa.)
ISSN: NIL (Print), eISSN: 1662-6575 (Online)

For additional information: http://www.karger.com/CRO


Article / Publication Details

First-Page Preview
Abstract of Published: November 2011

Published online: 11/22/2011

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 0

ISSN: (Print)
eISSN: 1662-6575 (Online)

For additional information: http://www.karger.com/CRO


Open Access License / Drug Dosage

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.