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Vol. 15, No. 3-4, 2012
Issue release date: April 2012
Section title: Paper
Public Health Genomics 2012;15:139–145
(DOI:10.1159/000335226)

The Role of Genomics in Health Behavior Change: Challenges and Opportunities

Bryan A.D. · Hutchison K.E.
Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colo., USA

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 4/4/2012
Issue release date: April 2012

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 1662-4246 (Print)
eISSN: 1662-8063 (Online)

For additional information: http://www.karger.com/PHG

Abstract

The most common causes of morbidity and mortality in the western world can be accounted for by unhealthy patterns of behavior (e.g. smoking, sedentary lifestyle, unhealthy diet, and alcohol consumption). Interventions to improve health behavior are sorely needed. To fully realize the potential of health behavior change interventions, be they individual level, community level, social structural, or policy-based, a greater understanding of the extent to which genomics can inform efforts at health behavior change is warranted. In this commentary, we explore three relatively novel possible routes to the integration of genomics and health behavior: (1) genomics may influence health behavior indirectly through intermediate phenotypes, requiring well-defined theory-based and mechanistic models of health behavior, (2) genomics may moderate response to interventions to change health behavior, and (3) genomics, specifically epigenetic variation, may be influenced by health behavior. The integration of genomics into research on interventions to change health behavior is not without challenges and will certainly require transdisciplinary collaborative science to succeed. We provide specific action points for moving the science forward to explore the extent to which genomic information can be harnessed to ultimately decrease morbidity and mortality associated with unhealthy behavior.


  

Author Contacts

Angela D. Bryan, PhD
Department of Psychology and Neuroscience
University of Colorado, UCB 345
Boulder, CO 80309-0345 (USA)
Tel. +1 303 492 8264, E-Mail angela.bryan@colorado.edu

  

Article Information

Published online: April 4, 2012
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 0, Number of References : 55

  

Publication Details

Public Health Genomics

Vol. 15, No. 3-4, Year 2012 (Cover Date: April 2012)

Journal Editor: Brand A.M. (Maastricht)
ISSN: 1662-4246 (Print), eISSN: 1662-8063 (Online)

For additional information: http://www.karger.com/PHG


Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: 4/4/2012
Issue release date: April 2012

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 1662-4246 (Print)
eISSN: 1662-8063 (Online)

For additional information: http://www.karger.com/PHG


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