Journal Mobile Options
Table of Contents
Vol. 4, No. 1, 2012
Issue release date: January – April
Add to my selection Citation Download
Open Access Gateway
Case Rep Dermatol 2012;4:50–55
(DOI:10.1159/000337196)
Published: March 2012

Cutaneous Lymphadenoma: A Case Report and Immunohistochemical Study

Fujimura T. · Itoigawa A. · Haga T. · Aiba S.
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan Case Rep Dermatol 2012;4:50–55 (DOI:10.1159/000337196)

Abstract

Cutaneous lymphadenoma is a rare neoplasm, and characterized by a florid mononuclear cell infiltration that appears to be an integral component of the tumor. Several reports suggested that these infiltrated lymphocytes mainly consist of T cells and Langerhans cells, but no detailed phenotypical analysis of these cells has been demonstrated yet. In this report, we describe a 70-year-old Japanese patient with cutaneous lymphadenoma. In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating cells in cutaneous lymphadenoma, especially focusing on the profiles of T cell subsets. In addition, there are abundant mucin deposits within the tumor stroma, and tumor lobules are composed of BerEP4-positive cells. To the best of our knowledge, this is the first report that employed immunohistochemical staining of cutaneous lymphadenoma to verify the types of cells composing such tumors with special focus on the profiles of the T cell subsets.

 goto top of outline Author Contacts

Taku Fujimura
Department of DermatologyTohoku University Graduate School of Medicine
Seiryo-machi 1-1, Aoba-ku, Sendai, 980-8574 (Japan)
Tel. +81 22 717 7271, E-Mail tfujimura1@mac.com


 goto top of outline Article Information

Published online: March 1, 2012
Number of Print Pages : 6
Number of Figures : 4,


 goto top of outline Publication Details

Case Reports in Dermatology

Vol. 4, No. 1, Year 2012 (Cover Date: January - April)

Journal Editor: Jemec G.B.E. (Roskilde)
ISSN: 1662-6567 (Print), eISSN: 1662-6567 (Online)

For additional information: http://www.karger.com/CDE


Open Access License / Drug Dosage

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.