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Vol. 6, No. 1, 2012
Issue release date: January – April
Section title: Published: March 2012

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Case Rep Gastroenterol 2012;6:135–142
(DOI:10.1159/000337870)

Endoscopic Management of a Primary Duodenal Carcinoid Tumor

Abraham A. · Singh J. · Siddiqui G. · Prasad A. · Rashid S. · Vardaros M. · Garg V. · Rizvon K. · Subramani K. · Mustacchia P.
Department of Internal Medicine, Nassau University Medical Center, East Meadow, N.Y., USA
email Corresponding Author

Albin Abraham

Department of Internal Medicine, Nassau University Medical Center

2201 Hempstead Turnpike, East Meadow, NY 11554 (USA)

Tel. +1 505 688 5451, E-Mail aabraha1@numc.edu

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Abstract

Carcinoids are rare, slow-growing tumors originating from a variety of different neuroendocrine cell types. They are identified histologically by their affinity for silver salts and by positive reactions to neuroendocrine markers such as neuron-specific enolase, synaptophysin and chromogranin. They can present with various clinical symptoms and are difficult to diagnose. We present the case of a 43-year-old woman who was referred for evaluation of anemia. Upper endoscopy showed a duodenal bulb mass around 1 cm in size. Histopathological and immunohistochemistry staining were consistent with the diagnosis of a carcinoid tumor. Further imaging and endoscopic studies showed no other synchronous carcinoid lesions. Endoscopic ultrasound (EUS) revealed a 1 cm lesion confined to the mucosa and no local lymphadenopathy. Successful endoscopic mucosal resection of the mass was performed. Follow-up surveillance 6 months later with EUS and Octreoscan revealed no new lesions suggestive of recurrence. No consensus guidelines exist for the endoscopic management of duodenal carcinoid tumors. However, endoscopic resection is safe and preferred for tumors measuring 1 cm or less with no evidence of invasion of the muscularis layer.

© 2012 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Published: March 2012

Published online: 3/23/2012
Issue release date: January – April

Number of Print Pages: 8
Number of Figures: 3
Number of Tables: 1

ISSN: (Print)
eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG


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