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Vol. 6, No. 1, 2012
Issue release date: January – April
Section title: Published: April 2012

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Case Rep Gastroenterol 2012;6:205–210

Prolonged Survival in a Patient with Neuroendocrine Tumor of the Cecum and Diffuse Peritoneal Carcinomatosis

de Mestier L.a · Neuzillet C.a · Hentic O.a · Kianmanesh R.b · Hammel P.a · Ruszniewski P.a
aService de Gastroentérologie-Pancréatologie and bService de Chirurgie Hépato-Biliaire, Pôle des Maladies de l’Appareil Digestif, Hôpital Beaujon (AP-HP and Université Paris VII – Denis Diderot), Clichy, France
email Corresponding Author

Prof. Pascal Hammel

Service de Gastroentérologie-PancréatologiePôle des Maladies de l’Appareil Digestif, Hôpital Beaujon (AP-HP)

100 boulevard Leclerc, FR–92110 Clichy (France)


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Peritoneal carcinomatosis is a well-known factor of poor prognosis in patients with digestive adenocarcinomas. Peritoneal dissemination may also occur in midgut well-differentiated neuroendocrine tumors, but its influence on survival is ill-defined. We report here the history of a 64-year-old woman who had a neuroendocrine tumor of the cecum with multiple synchronous metastases in the liver and diffuse peritoneal carcinomatosis. She underwent surgical resection of the primary tumor and cytoreduction of liver metastases, and received subsequently chemotherapy and somatostatin analogs. In spite of the widespread extension of the disease, she survived for 13 years and died from a carcinoid heart disease. We discuss the natural history and prognostic factors in patients with midgut well-differentiated neuroendocrine tumors, with a focus on the impact of the peritoneal carcinomatosis.

© 2012 S. Karger AG, Basel

Article / Publication Details

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Abstract of Published: April 2012

Published online: 4/30/2012
Issue release date: January – April

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 2

ISSN: (Print)
eISSN: 1662-0631 (Online)

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