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Table of Contents
Vol. 39, No. 1, 2012
Issue release date: July 2012
Section title: Original Paper
Neuroepidemiology 2012;39:57–62
(DOI:10.1159/000339362)

Stroke in the Very Elderly: Characteristics and Outcome in Patients Aged ≥85 Years with a First-Ever Ischemic Stroke

Gur A.Y.a · Tanne D.b, d · Bornstein N.M.c, d · Milo R.a · Auriel E.c, d · Shopin L.c, d · Koton S.d · on behalf of the NASIS Investigators
aDepartment of Neurology, Barzilai Medical Center, Ashkelon, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, and Departments of Neurology, bSheba Medical Center, cTel-Aviv Sourasky Medical Center, and dThe Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: March 12, 2012
Accepted: May 07, 2012
Published online: July 08, 2012
Issue release date: July 2012

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 4

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: http://www.karger.com/NED

Abstract

Background: Epidemiological and clinical features of very elderly patients with stroke are still uncertain. Our aim was to study the patient characteristics and outcomes in the very elderly (aged ≥85 years) with a first-ever ischemic stroke in the National Acute Stroke Israeli Survey (NASIS) registry. Methods: The NASIS registry is a nationwide prospective hospital-based study performed triennially (2004, 2007, 2010). Patients with ischemic stroke aged ≥85 years were compared with those 65–84 years old regarding their baseline characteristics, stroke severity, etiology of stroke and stroke outcomes. Logistic regression analyses were used to adjust for potential confounders. Stroke severity was determined according to the National Institute of Health Stroke Scale (NIHSS) score. Results: The proportion of very elderly (≥85 years) patients among the NASIS population increased from 18.3% in 2004 to 19.9% in 2007 and 24.5% in 2010 (p for trend = 0.005). The percentage of women was higher in patients aged ≥85 years (p < 0.0001). Atrial fibrillation, congestive heart disease and prior disability were significantly more common, while diabetes, current smoking and dyslipidemia were less frequent in the very elderly. The very elderly presented with more severe strokes: 36.3% of the ≥85-year-old patients had an NIHSS score ≥11 compared with 22.0% in the younger age group (p < 0.05). Conclusions: There is an increasing proportion of very elderly subjects, mostly women, among first-ever ischemic stroke patients. Current information on age-specific aspects of stroke in the very elderly is crucial to set up successful prevention pathways and implementing well-organized stroke care for this population.

© 2012 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: March 12, 2012
Accepted: May 07, 2012
Published online: July 08, 2012
Issue release date: July 2012

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 4

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: http://www.karger.com/NED


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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