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Vol. 33, No. 5, 2012
Issue release date: July 2012
Section title: Original Research Article
Dement Geriatr Cogn Disord 2012;33:354–360
(DOI:10.1159/000339670)

Activities of Daily Living in Progressive Non-Fluent Aphasia, Logopenic Progressive Aphasia and Alzheimer’s Disease

Jang J. · Cushing N. · Clemson L. · Hodges J.R. · Mioshi E.
Neuroscience Research Australia, Sydney, Australia

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Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: 5/22/2012
Published online: 7/10/2012
Issue release date: July 2012

Number of Print Pages: 7
Number of Figures: 3
Number of Tables: 2

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

Abstract

Background/Aims: This study examined functional changes in progressive non-fluent aphasia (PNFA) and logopenic progressive aphasia (LPA) and Alzheimer’s disease (AD) and the association between function, cognition and behaviour. Methods: 59 patients were assessed with the Disability Assessment of Dementia (DAD), Addenbrooke’s Cognitive Examination Revised (ACE-R) and the Cambridge Behavioural Inventory Revised (CBI-R). Results: No differences between groups in basic and instrumental activities of daily living (ADLs), and total ACE-R scores were found; there were correlations between total DAD and ACE-R scores for PNFA and LPA. Over 12 months, PNFA showed the marked decline of basic ADLs, whereas all three groups showed marked decline of instrumental ADLs. Conclusion: PNFA, LPA and AD appear functionally similar when matched for disease duration. The rate of decline of ADLs depends, however, on disease diagnosis.

© 2012 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: 5/22/2012
Published online: 7/10/2012
Issue release date: July 2012

Number of Print Pages: 7
Number of Figures: 3
Number of Tables: 2

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


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