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Vol. 89, No. 3, 2012
Issue release date: October 2012
Section title: Original Paper
Urol Int 2012;89:307–310
(DOI:10.1159/000339920)

Ureteral Stenting in Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy as a Routine Procedure: Evidence and Necessity

Coccolini F. · Lotti M. · Manfredi R. · Catena F. · Vallicelli C. · De Iaco P.A. · Da Pozzo L. · Frigerio L. · Ansaloni L.
Departments of aGeneral and Emergency Surgery, bUrology, and cObstetrics and Gynecology, Ospedali Riuniti, Bergamo, and Departments of dGeneral and Transplant Surgery, and eObstetrics and Gynecology, Sant’Orsola-Malpighi University Hospital, Bologna, Italy

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/18/2012
Accepted: 5/28/2012
Published online: 8/1/2012

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: http://www.karger.com/UIN

Abstract

Introduction: There is a need for more exhaustive data concerning the use of prophylactic ureteral stenting for extended debulking and cytoreductive procedures in the literature. Material and Methods: A retrospective analysis of the CARPEPACEM study protocol database was performed. The trial protocol schedules the positioning of bilateral ureteral stents before cytoreductive surgery + hyperthermic intraperitoneal chemotherapy (HIPEC). Results: Fifty-one operated patients: 31 (59.6%) with peritoneal dissemination from ovarian cancer, 8 (15.3%) from colorectal cancer, 4 (7.9%) from pseudomyxoma peritonei, 3 (5.7%) from gastric cancer, 2 (3.8%) from peritoneal mesothelioma, 1 (1.9%) from appendiceal cancer, 1 (1.9%) from endometrial cancer, and 1 (1.9%) from leiomyosarcoma. Mean and median peritoneal cancer index: 11 and 10 (range: 0–28). CC-score: CC-0 in 45 (86.5%) patients, CC-1 in 5 (9.6%) and CC-2 in 1 (1.9%). HIPEC was performed with platinum + taxol in 22 patients (42.3%), platinum + adriablastin in 10 (19.2%), mitomycin in 9 (17.3%), platinum + mitomycin in 7 (13.4%), platinum + doxorubicin in 2 (3.8%), and taxol + adriablastin in 1 (1.9%). Two major ureteral complications were observed (3.9%). Discussion: Prophylactic ureteral stenting could reduce the risk of postoperative ureteral complications without an increase in stent placement-related complications; however, a randomized clinical trial is needed.


  

Author Contacts

Coccolini Federico, MD
General and Emergency Surgery Department
Ospedali Riuniti, Largo Barozzi 1
IT–24128 Bergamo (Italy)
Tel. +39 035 266 515/035 266 464, E-Mail fedecocco@iol.it

  

Article Information

Received: January 18, 2012
Accepted after revision: May 28, 2012
Published online: August 1, 2012
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 0, Number of References : 30

  

Publication Details

Urologia Internationalis

Vol. 89, No. 3, Year 2012 (Cover Date: October 2012)

Journal Editor: Wirth M.P. (Dresden), Porena M. (Perugia), Hakenberg O.W. (Rostock), Castro-Diaz D. (Santa Cruz de Tenerife), Wullich B. (Erlangen)
ISSN: 0042-1138 (Print), eISSN: 1423-0399 (Online)

For additional information: http://www.karger.com/UIN


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 1/18/2012
Accepted: 5/28/2012
Published online: 8/1/2012

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: http://www.karger.com/UIN


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