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Primary Burkitt’s Lymphoma Presenting as a Rapidly Growing Thyroid MassYildiz I.a · Sen F.a · Toz B.b · Kilic L.a · Agan M.c · Basaran M.a
aDepartment of Medical Oncology, Institute of Oncology, and Departments of bInternal Medicine and cPathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey Corresponding Author
Ibrahim Yildiz, MD
Department of Medical Oncology
Institute of Oncology, Istanbul University
TR–21234 Istanbul (Turkey)
Tel. +90 505 746 51 78, E-Mail firstname.lastname@example.org
A 31-year-old male patient presented with a rapidly growing neck mass with normal thyroid function tests. Ultrasonography showed thyroidal expansion, a hypoechoic nodule that completely filled the right lobe, and 2 hypoechoic lymphadenopathies in the right jugulodigastric chain. The patient underwent right total and left subtotal thyroidectomy, following the diagnosis of nodular goiter; however, postoperative histopathological evaluation demonstrated primary Burkitt’s lymphoma of the thyroid gland. The tumor was staged as stage 1, and R-hyper-CVAD protocol (rituximab, hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone) was administered. The protocol was changed to R-CHOP after 4 cycles due to recurrent grade III/IV cytopenias and febrile neutropenia. The PET-CT scans performed after chemotherapy and at the 6-month follow-up were normal. In summary, we reported a case with a diagnosis of Burkitt’s lymphoma, which is a rare type of primary thyroid lymphoma.
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