Primary Burkitt’s Lymphoma Presenting as a Rapidly Growing Thyroid MassYildiz I. · Sen F. · Toz B. · Kilic L. · Agan M. · Basaran M.
aDepartment of Medical Oncology, Institute of Oncology, and Departments of bInternal Medicine and cPathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
A 31-year-old male patient presented with a rapidly growing neck mass with normal thyroid function tests. Ultrasonography showed thyroidal expansion, a hypoechoic nodule that completely filled the right lobe, and 2 hypoechoic lymphadenopathies in the right jugulodigastric chain. The patient underwent right total and left subtotal thyroidectomy, following the diagnosis of nodular goiter; however, postoperative histopathological evaluation demonstrated primary Burkitt’s lymphoma of the thyroid gland. The tumor was staged as stage 1, and R-hyper-CVAD protocol (rituximab, hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone) was administered. The protocol was changed to R-CHOP after 4 cycles due to recurrent grade III/IV cytopenias and febrile neutropenia. The PET-CT scans performed after chemotherapy and at the 6-month follow-up were normal. In summary, we reported a case with a diagnosis of Burkitt’s lymphoma, which is a rare type of primary thyroid lymphoma.
Ibrahim Yildiz, MD
Department of Medical Oncology
Institute of Oncology, Istanbul University
TR–21234 Istanbul (Turkey)
Tel. +90 505 746 51 78, E-Mail email@example.com
Published online: July 24, 2012
Number of Print Pages : 6
Number of Figures : 2,
Case Reports in Oncology
Vol. 5, No. 2, Year 2012 (Cover Date: May - August)
Journal Editor: Markman M. (Philadelphia, Pa.)
ISSN: 1662-6575 (Print), eISSN: 1662-6575 (Online)
For additional information: http://www.karger.com/CRO