Introduction: Quality assurance in health care involves the evaluation of outcomes, cost-benefit ratios, and access to the delivery system. This literature review was undertaken to clarify the incidence of serious posttonsillectomy complications to better understand the outcome component of quality assurance. Material and Methods: A Medline review was undertaken using the key word ‘tonsillectomy' AND each of the following: ‘serious', ‘complications' and ‘review'; ‘meta-analysis', ‘Cochrane'; ‘life-threatening', ‘death' and ‘disability'. Results: 454 articles were identified with the following search items in combination with ‘tonsillectomy': ‘serious' (154), ‘complications', ‘review' (24), ‘meta-analysis' (38), ‘Cochrane' (43), ‘life-threatening' (87), ‘death' (91), ‘disability' (17). Sixty-seven articles described a complication rate and were therefore eligible for review: 22 case reports, 9 case series, 2 questionnaires and 33 studies with a more or less precise complication rate were obtainable. Most articles (n = 30) reported the rate of posttonsillectomy hemorrhage with a considerable range. Fifteen articles reported the incidence of death, which ranged from 1:7,132 to 1:170,000 and almost always resulted from excessive hemorrhage. All other complications were mentioned in case reports. Conclusion: The most common postoperative complication of tonsillectomy is bleeding. However, the incidence varies considerably across studies depending on the study design, follow-up and definition of postoperative bleeding. Other serious adverse events, such as neurological disabilities, emphysema (with or without pneumomediastinum), or vascular problems outside the neck are infrequent.

1.
Boss EF, Marsteller JA, Simon AE: Outpatient tonsillectomy in children: demographic and geographic variation in the United States, 2006. J Pediatr 2011;160:814-819.
3.
Weil-Olivier C, Sterkers G, Francois M, et al: Tonsillectomy in 2005 (in French). Arch Pediatr 2006;13:168-174.
4.
Vestergaard H, Wohlfahrt J, Westergaard T, et al: Incidence of tonsillectomy in Denmark, 1980 to 2001. Pediatr Infect Dis J 2007;26:1117-1121.
5.
Stalfors J, Ericsson E, Hemlin C, et al: Tonsil surgery efficiently relieves symptoms: analysis of 54,696 patients in the National Tonsil Surgery Register in Sweden. Acta Otolaryngol 2012;132:533-539.
6.
Sarny S, Ossimitz G, Habermann W, et al: Hemorrhage following tonsil surgery: a multicenter prospective study. Laryngoscope 2011;121:2553-2560.
7.
Dindo D, Demartines N, Clavien PA: Classification of surgical complications. A new proposal with evaluation in a cohort of 6,336 patients and results of a survey. Ann Surg 2004;240:205-213.
8.
Windfuhr JP, Schloendorff G, Baburi D, et al: Life-threatening posttonsillectomy hemorrhage. Laryngoscope 2008;118:1389-1394.
9.
McKenna M: Postoperative tonsillectomy/adenoidectomy hemorrhage: a retrospective chart review. ORL Head Neck Nurs 1999;17:18-21.
10.
Van Gelder L: Open nasal speech following adenoidectomy and tonsillectomy. J Commun Disord 1974;7:263-267.
11.
Attner P, Haraldsson PO, Hemlin C, et al: A 4-year consecutive study of post-tonsillectomy haemorrhage. ORL J Otorhinolaryngol Relat Spec 2009;71:273-278.
12.
Gardner JF: Sutures and disasters in tonsillectomy. Arch Otolaryngol 1968;88:551-555.
13.
Windfuhr JP, Schloendorff G, Sesterhenn AM, et al: A devastating outcome after adenoidectomy and tonsillectomy: ideas for improved prevention and management. Otolaryngol Head Neck Surg 2009;140:191-196.
14.
Windfuhr JP, Chen YS, Remmert S: Hemorrhage following tonsillectomy and adenoidectomy in 15,218 patients. Otolaryngol Head Neck Surg 2005;132:281-286.
15.
Windfuhr JP: Indications for interventional arteriography in post-tonsillectomy hemorrhage. J Otolaryngol 2002;31:18-22.
16.
Windfuhr J, Seehafer M: Classification of haemorrhage following tonsillectomy. J Laryngol Otol 2001;115:457-461.
17.
Guida RA, Mattucci KF: Tonsillectomy and adenoidectomy: an inpatient or outpatient procedure? Laryngoscope 1990;100:491-493.
18.
Kang J, Brodsky L, Danziger I, et al: Coagulation profile as a predictor for post-tonsillectomy and adenoidectomy (T + A) hemorrhage. Int J Pediatr Otorhinolaryngol 1994;28:157-165.
19.
Richmond KH, Wetmore RF, Baranak CC: Postoperative complications following tonsillectomy and adenoidectomy - who is at risk? Int J Pediatr Otorhinolaryngol 1987;13:117-124.
20.
Handler SD, Miller L, Richmond KH, et al: Post-tonsillectomy hemorrhage: incidence, prevention and management. Laryngoscope 1986;96:1243-1247.
21.
Watson MG, Dawes PJ, Samuel PR, et al: A study of haemostasis following tonsillectomy comparing ligatures with diathermy. J Laryngol Otol 1993;107:711-715.
22.
Morris LG, Lieberman SM, Reitzen SD, et al: Characteristics and outcomes of malpractice claims after tonsillectomy. Otolaryngol Head Neck Surg 2008;138:315-320.
23.
Stevenson AN, Myer CM 3rd, Shuler MD, et al: Complications and legal outcomes of tonsillectomy malpractice claims. Laryngoscope 2012;122:71-74.
24.
Krishna P, La Page MJ, Hughes LF, et al: Current practice patterns in tonsillectomy and perioperative care. Int J Pediatr Otorhinolaryngol 2004;68:779-784.
25.
Lowe D, van der Meulen J: National prospective tonsillectomy audit: tonsillectomy technique as a risk factor for postoperative hemorrhage. Lancet 2004;364:642-643.
26.
Hessen Soderman AC, Ericsson E, Hemlin C, et al: Reduced risk of primary postoperative hemorrhage after tonsil surgery in Sweden: results from the National Tonsil Surgery Register in Sweden covering more than 10 years and 54,696 operations. Laryngoscope 2011;121:2322-2326.
27.
Windfuhr JP, Wienke A, Chen YS: Electrosurgery as a risk factor for secondary post-tonsillectomy hemorrhage. Eur Arch Otorhinolaryngol 2009;266:111-116.
28.
Pinder DK, Wilson H, Hilton MP: Dissection versus diathermy for tonsillectomy. Cochrane Database Syst Rev 2011;3:CD002211.
29.
Macassey EA, Baguley C, Dawes P, et al: 15-year audit of post-tonsillectomy haemorrhage at Dunedin Hospital. Aust NZ J Surg 2007;77:579-582.
30.
Heidemann CH, Wallen M, Aakesson M, et al: Post-tonsillectomy hemorrhage: assessment of risk factors with special attention to introduction of coblation technique. Eur Arch Otorhinolaryngol 2009;266:1011-1015.
31.
Lowe D, van der Meulen J: Tonsillectomy technique as a risk factor for postoperative haemorrhage. Lancet 2004;364:697-702.
32.
Lowe D, van der Meulen J, Cromwell D, et al: Key messages from the National Prospective Tonsillectomy Audit. Laryngoscope 2007;117:717-724.
33.
Arnoldner C, Grasl M, Thurnher D, et al: Surgical revision of hemorrhage in 8,388 patients after cold-steel adenotonsillectomies. Wien Klin Wochenschr 2008;120:336-342.
34.
Windfuhr J, Chen Y, Remmert S: Hemorrhage following tonsillectomy and adenoidectomy in 15,214 patients. Otolaryngol Head Neck Surg 2005;132:281-286.
35.
Rasmussen N: Complications of tonsillectomy and adenoidectomy. Otolaryngol Clin North Am 1987;20:383-390.
36.
Windfuhr JP, Schlondorff G, Sesterhenn AM, et al: From the expert's office: localized neural lesions following tonsillectomy. Eur Arch Otorhinolaryngol 2009;266:1621-1640.
37.
Windfuhr JP, Sesterhenn AM, Schloendorff G, et al: Post-tonsillectomy pseudoaneurysm: an underestimated entity? J Laryngol Otol 2010;124:59-66.
38.
Yu KK, White DR, Weissler MC, et al: Nontraumatic atlantoaxial subluxation (Grisel syndrome): a rare complication of otolaryngological procedures. Laryngoscope 2003;113:1047-1049.
39.
Stewart AE, Brewster DF, Bernstein PE: Subcutaneous emphysema and pneumomediastinum complicating tonsillectomy. Arch Otolaryngol Head Neck Surg 2004;130:1324-1327.
40.
McSeveny WR: A report on an inquiry into the death of a 5 years old boy during an operation for removal of tonsils and adenoids. Lamp 1977;34:23.
41.
McRae R, Weissburg A, Chang K: Iatrogenic hyponatremia: a cause of death following pediatric tonsillectomy. Int J Pediatr Otorhinolaryngol 1994;30:227-232.
42.
Peeters A, Claes J, Saldien V: Lethal complications after tonsillectomy. Acta Otorhinolaryngol Belg 2001;55:207-213.
43.
Byard RW: Tonsillitis and sudden childhood death. J Forensic Leg Med 2008;15:516-518.
44.
Smith ME: Death from tonsillectomy. Lancet 1959;i:671-672.
45.
Taylor GW: Death following tonsillectomy. AMA Arch Otolaryngol 1950;52:642-645.
46.
Windfuhr JP: Lethal post-tonsillectomy hemorrhage. Auris Nasus Larynx 2003;30:391-396.
47.
Windfuhr JP, Schloendorff G, Baburi D, et al: Lethal outcome of post-tonsillectomy hemorrhage. Eur Arch Otorhinolaryngol 2008;265:1527-1534.
48.
Windfuhr JP, Schloendorff G, Baburi D, et al: Serious post-tonsillectomy hemorrhage with and without lethal outcome in children and adolescents. Int J Pediatr Otorhinolaryngol 2008;72:1029-1040.
49.
Ford L, Cruz R: Bilateral glossopharyngeal nerve paralysis after tonsillectomy: case report and anatomic study. Laryngoscope 2004;114:2196-2199.
50.
Miman MC, Ozturan O, Durmus M, et al: Cervical subcutaneous emphysema: an unusual complication of adenotonsillectomy. Paediatr Anaesth 2001;11:491-493.
51.
Shine NP, Sader C, Coates H: Cervicofacial emphysema and pneumomediastinum following pediatric adenotonsillectomy: a rare complication. Int J Pediatr Otorhinolaryngol 2005;69:1579-1582.
52.
Samuel D, Thomas DM, Tierney PA, et al: Atlanto-axial subluxation (Grisel's syndrome) following otolaryngological diseases and procedures. J Laryngol Otol 1995;109:1005-1009.
53.
Hofman R, Zeebregts CJ, Dikkers FG: Fulminant post-tonsillectomy haemorrhage caused by aberrant course of the external carotid artery. J Laryngol Otol 2005;119:655-657.
54.
Opatowsky MJ, Browne JD, McGuirt WF Jr, et al: Endovascular treatment of hemorrhage after tonsillectomy in children. AJNR Am J Neuroradiol 2001;22:713-716.
55.
Bolger WE, Parsons DS, Potempa L: Preoperative hemostatic assessment of the adenotonsillectomy patient. Otolaryngol Head Neck Surg 1990;103:396-405.
56.
Schrock A, Jakob M, Strach K, et al: Transarterial endovascular treatment in the management of life-threatening intra- and postoperative haemorrhages after otorhinolaryngological surgery. Eur Arch Otorhinolaryngol 2012;269:1677-1683.
57.
Bidlingmaier C, Olivieri M, Stelter K, et al: Postoperative bleeding in paediatric ENT surgery. First results of the German ESPED trial. Hamostaseologie 2010;30(suppl 1):S108-S111.
58.
Nuara MJ, Park AH, Alder SC, et al: Perioral burns after adenotonsillectomy: a potentially serious complication. Arch Otolaryngol Head Neck Surg 2008;134:10-15.
59.
Thomas CL, Palmer TJ, Shipley P: Negative pressure pulmonary edema after a tonsillectomy and adenoidectomy in a pediatric patient: case report and review. AANA J 1999;67:425-430.
60.
Leonard IE, Lacy PD, Moriarty DC, et al: Pulmonary embolism following tonsillectomy. J Laryngol Otol 2001;115:823-825.
61.
Goins MR, Pitovski DZ: Posttonsillectomy taste distortion: a significant complication. Laryngoscope 2004;114:1206-1213.
62.
Randall DA: Taste impairment following tonsillectomy and adenoidectomy: an unusual complication. Ear Nose Throat J 2010;89:E15-E18.
63.
Pourhassan S, Grotemeyer D, Fokou M, et al: Extracranial carotid arteries aneurysms in children: single-center experiences in 4 patients and review of the literature. J Pediatr Surg 2007;42:1961-1968.
64.
Wraige E, Ganesan V, Pohl KR: Arterial dissection complicating tonsillectomy. Dev Med Child Neurol 2003;45:638-639.
65.
Leong SC, Karkos PD, Papouliakos SM, et al: Unusual complications of tonsillectomy: a systematic review. Am J Otolaryngol 2007;28:419-422.
66.
Cohen D, Dor M: Morbidity and mortality of post-tonsillectomy bleeding: analysis of cases. J Laryngol Otol 2008;122:88-92.
67.
Alexander RJ, Kukreja R, Ford GR: Secondary post-tonsillectomy haemorrhage and informed consent. J Laryngol Otol 2004;118:937-940.
68.
Alexiou VG, Salazar-Salvia MS, Jervis PN, et al: Modern technology-assisted vs conventional tonsillectomy: a meta-analysis of randomized controlled trials. Arch Otolaryngol Head Neck Surg 2011;137:558-570.
69.
Amir I, Belloso A, Broomfield SJ, et al: Return to theatre in secondary post-tonsillectomy haemorrhage: a comparison of coblation and dissection techniques. Eur Arch Otorhinolaryngol 2012;269:667-671.
70.
Attner P, Haraldsson PO, Hemlin C, et al: A 4-year consecutive study of post-tonsillectomy haemorrhage. ORL J Otorhinolaryngol Relat Spec 2009;71:273-278.
71.
Brigger MT, Brietzke SE: Outpatient tonsillectomy in children: a systematic review. Otolaryngol Head Neck Surg 2006;135:1-7.
72.
Burton MJ, Doree C: Coblation versus other surgical techniques for tonsillectomy. Cochrane Database Syst Rev 2007;3:CD004619.
73.
Cardwell M, Siviter G, Smith A: Non-steroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy. Cochrane Database Syst Rev 2005;2:CD003591.
74.
Chiang TM, Sukis AE, Ross DE: Tonsillectomy performed on an outpatient basis. Report of a series of 40,000 cases performed without a death. Arch Otolaryngol 1968;88:307-310.
75.
Dhiwakar M, Clement WA, Supriya M, et al: Antibiotics to reduce post-tonsillectomy morbidity. Cochrane Database Syst Rev 2010;7:CD005607.
76.
Diakos EA, Gallos ID, El-Shunnar S, et al: Dexamethasone reduces pain, vomiting and overall complications following tonsillectomy in adults: a systematic review and meta-analysis of randomised controlled trials. Clin Otolaryngol 2011;36:531-542.
77.
Evans A, Khan A, Young D, et al: Assessment of secondary haemorrhage rates following adult tonsillectomy - a telephone survey and literature review. Clin Otolaryngol 2003;28:489-491.
78.
Kristensen S, Tveteras K: Post-tonsillectomy haemorrhage. A retrospective study of 1,150 operations. Clin Otolaryngol Allied Sci 1984;9:347-350.
79.
Laureyns G, Lemkens P, Jorissen M: Tonsillectomy as a day-case surgery: a safe procedure? B-ENT 2006;2:109-116.
80.
Marret E, Flahault A, Samama CM, et al: Effects of postoperative, nonsteroidal, antiinflammatory drugs on bleeding risk after tonsillectomy: meta-analysis of randomized, controlled trials. Anesthesiology 2003;98:1497-1502.
81.
Moiniche S, Romsing J, Dahl JB, et al: Nonsteroidal antiinflammatory drugs and the risk of operative site bleeding after tonsillectomy: a quantitative systematic review. Anesth Analg 2003;96:68-77.
82.
Moralee SJ, Murray JA: Would day-case adult tonsillectomy be safe? J Laryngol Otol 1995;109:1166-1167.
83.
Mösges R, Hellmich M, Allekotte S, et al: Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trials. Eur Arch Otorhinolaryngol 2011;268:807-816.
84.
Mowatt G, Cook JA, Fraser C, et al: Systematic review of the safety of electrosurgery for tonsillectomy. Clin Otolaryngol 2006;31:95-102.
85.
Ovesen T, Kamarauskas G, Dahl M, et al: Pain and bleeding are the main determinants of unscheduled contacts after outpatient tonsillectomy. Dan Med J 2012;59:A4382.
86.
Salonen A, Kokki H, Nuutinen J: Recovery after tonsillectomy in adults: a three-week follow-up study. Laryngoscope 2002;112:94-98.
87.
Tomkinson A, De Martin S, Gilchrist CR, et al: Instrumentation and patient characteristics that influence postoperative haemorrhage rates following tonsil and adenoid surgery. Clin Otolaryngol 2005;30:338-346.
88.
Tomkinson A, Harrison W, Owens D, et al: Risk factors for postoperative hemorrhage following tonsillectomy. Laryngoscope 2011;121:279-288.
89.
Wagner GA: Ambulatory adult tonsillectomy. J Otolaryngol 1991;20:33-34.
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