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Table of Contents
Vol. 91, No. 1, 2013
Issue release date: January 2013
Section title: Clinical Study
Stereotact Funct Neurosurg 2013;91:56–65
(DOI:10.1159/000343202)

The Risk of Hardware Infection in Deep Brain Stimulation Surgery Is Greater at Impulse Generator Replacement than at the Primary Procedure

Pepper J.a · Zrinzo L.a · Mirza B.a · Foltynie T.a · Limousin P.a · Hariz M.a, b
aUnit of Functional Neurosurgery, UCL Institute of Neurology, London, UK; bDepartment of Clinical Neuroscience, Umeå University, Umeå, Sweden

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Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Received: May 22, 2012
Accepted: September 04, 2012
Published online: November 29, 2012
Issue release date: January 2013

Number of Print Pages: 10
Number of Figures: 2
Number of Tables: 4

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: http://www.karger.com/SFN

Abstract

Background/Aims: Infection of implanted hardware after deep brain stimulation (DBS) has a significant impact on patient morbidity. We examined all patients who underwent DBS procedures over the last 9 years in our centre to assess the infection rate and possible factors related to surgery that may predispose to infection. Methods: Surgical reports and clinical notes were reviewed in 273 consecutive patients who underwent a total of 519 DBS-related procedures in our institute between November 2002 and September 2011. Results: Sixteen separate hardware-related infections occurred in 11 patients. Infections occurred in 3% of all procedures and 4% of all patients. The infection rate after implantable pulse generator (IPG) replacement surgery was more than three times higher than after de novo DBS surgery. In addition, male patients were more likely to develop device-related infections. Conclusions: It is unclear why infection rates should be more than three times higher after IPG replacement surgery than after the de novo procedure. The former is a shorter and simpler procedure to conduct. Perhaps the use of better antimicrobial protection and rechargeable batteries may be useful strategies to reduce infections following IPG revision surgery.

© 2012 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Received: May 22, 2012
Accepted: September 04, 2012
Published online: November 29, 2012
Issue release date: January 2013

Number of Print Pages: 10
Number of Figures: 2
Number of Tables: 4

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: http://www.karger.com/SFN


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