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7, No. 5, 2012
Issue release date: October 2012
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Breast Care 2012;7:364–369
Review Article · Übersichtsarbeit

Extent of Primary Breast Cancer Surgery: Standards and Individualized Concepts

Heil J.a · Fuchs V.a · Golatta M.a · Schott S.a · Wallwiener M.a · Domschke C.a · Sinn P.b · Lux M.P.c · Sohn C.a · Schütz F.a
aUniversitäts-Frauenklinik, Universitätsklinikum Heidelberg, bInstitut für Pathologie, Universität Heidelberg, cUniversitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Germany Breast Care 2012;7:364–369 (DOI:10.1159/000343976)


Surgery is still a main therapeutic option in breast cancer treatment. Nowadays, methods of resection and reconstruction vary according to different tumors and patients. This review presents and discusses standards of care and arising questions on how radical primary breast cancer surgery should be according to different clinical situations. In most early breast cancer patients, breast conservation is the method of choice. The discussion on resection margins is still controversial as different studies show conflicting results. Modified radical mastectomy is the standard in locally advanced breast cancer patients, although there are different promising approaches to spare skin or even the nipple-areola complex. A sentinel node biopsy is the standard of care in clinically node-negative invasive breast cancer patients, whereas the significance of axillary lymphonodectomy seems to be questioned through a number of different findings. Although there are interesting findings to modify surgical approaches in very young or elderly breast cancer patients, it will always be an individualized approach if we do not adhere to current guidelines. Up to date, there are no special surgical procedures in BRCA mutation carriers or patients of high-risk families.

 goto top of outline Author Contacts

PD Dr. Joerg Heil
Universitätsklinikum Heidelberg
Voßstrasse 9, 69115 Heidelberg, Germany

 goto top of outline Article Information

Published online: October 22, 2012
Number of Print Pages : 6

 goto top of outline Publication Details

Breast Care (Multidisciplinary Journal for Research, Diagnosis and Therapy)

Vol. 7, No. 5, Year 2012 (Cover Date: October 2012)

Journal Editor: Harbeck N. (München), Thomssen C. (Halle/Saale), Gnant M. (Wien)
ISSN: 1661-3791 (Print), eISSN: 1661-3805 (Online)

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